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  1. No Access

    Article

    Receptors of glutamate and neurotrophin in vestibular neuronal functions

    The last decade has witnessed advances in understanding the roles of receptors of neurotrophin and glutamate in the vestibular system. In the first section of this review, the biological actions of neurotrophi...

    Prof. Y. S. Chan, L. W. Chen, C. H. Lai, D. K. Y. Shum… in Journal of Biomedical Science (2003)

  2. No Access

    Article

    Bilateral otolith contribution to spatial coding in the vestibular system

    Recent work on the coding of spatial information in central otolith neurons has significantly advanced our knowledge of signal transformation from head-fixed otolith coordinates to space-centered coordinates d...

    Prof. Y. S. Chan, C. H. Lai, D. K. Y. Shum in Journal of Biomedical Science (2002)

  3. No Access

    Article

    Calcium oxalate crystallizing properties of polyanions elaborated by cultured renal proximal tubular cells

    To study the influence of renal polyanions on crystallization of urinary calcium oxalate, we recovered polyanionic macromolecules from media conditioned by primary cultures of renal proximal tubular epithelial...

    D. K. Y. Shum, E. Liong in Urological Research (1995)

  4. No Access

    Chapter

    Calcium Oxalate Crystallizing Properties of Macromolecules Released by Renal Tubular Cells in Vitro

    Urinary proteins and glycosaminoglycans (GAGs) have been shown to act diversely on the crystallization of calcium oxalate. In media where these macromolecules coexist as solubilized and immobilized forms, they...

    D. K. Y. Shum, E. Liong in Urolithiasis 2 (1994)

  5. No Access

    Chapter

    Urinary Glycosaminoglycans Differ in their Calcium Oxalate Crystallization Activities

    Various studies have indicated that urinary macromolecules exhibit diverse activities towards calcium oxalate crystallization1, 2. One group of these macromolecules, the glycosaminoglycans (GAGs), has been shown ...

    M. D. I. Gohel, D. K. Y. Shum in Urolithiasis 2 (1994)

  6. No Access

    Article

    The dual effect of urinary macromolecules on the crystallization of calcium oxalate endogenous in urine

    The nucleation-promoting and growth-inhibiting activities of urinary macromolecules on the crystallization of calcium oxalate endogenous in urine of stoneformers and normal controls were studied by freezing th...

    M. D. Gohel, D. K. Y. Shum, M. K. Li in Urological Research (1992)

  7. No Access

    Chapter

    Ultrafiltration Studies Demonstrate Effects of Urinary Macromolecules on Crystallization of Endogenous Calcium Oxalate in Urine

    An earlier study (1) suggested that urinary macromolecules capable of inducing nucleation and inhibiting growth of calcium oxalate (CaOx) crystals occur with a higher incidence in urine samples from stone form...

    D. K. Y. Shum, M. D. Gohel, M. K. Li in Urolithiasis (1989)

  8. No Access

    Article

    Detection of crystallization inhibitory activity of whole urine with a gel model

    The inhibitory activity of urine on calcium oxalate crystallization was measured as an inhibitory index using a gel model modified from Schneider et al. [8]. Urine samples from 36 recurrent stone formers and 2...

    Dr. M. K. Li, D. K. Y. Shum, S. Choi in Urological Research (1987)