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Arrythythmias in hypertrophic cardiomyopathy: prognostic significance and clinical relevance
Eighty patients with hypertrophic cardiomyopathy were studied for the presence of ventricular and supraventricular arrhythmias by 24-hour ambulatory electrocardiography. Ventricular tachycardia was present in ...
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Article
Abstracts of papers clinical pharmacological meeting
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Article
Abstracts of papers and posters
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Article
Dose-finding study of imidapril, a novel angiotensin converting enzyme inhibitor, in patients with stable chronic heart failure
Objective: To study the haemodynamic profile and tolerability of imidapril, a new long-acting ACE inhibitor, and to investigate the effect of inhibition of circulating ACE on blood press...
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Chapter
The Role of Vascular Failure in Heart Failure
Next to important adaptation mechanisms such as changes in the autonomic nervous system and humoral systems (e.g. the renin-angiotensin system), changes in the vascular wall play an important role in heart fai...
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Article
Quantitative assessment of the pressure and volume overloaded right ventricle: imaging is a real challenge
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Article
Evaluation of right ventricular function by NuSMUGA software: gated blood-pool SPECT vs. first-pass radionuclide angiography
Background: In comparison with planar imaging gated blood-pool single photon emission computed tomography (GBPS) has the advantage of separating left and right ventricle. The purpose of this investigation was to...
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Article
Heart failure and statins—Why do we need a clinical trial?
Der Effekt einer Therapie mit Statinen auf die Morbidität und Sterblichkeit ist bei Patienten in der Sekundärund Primärprävention sowie bei Patienten mit akutem Koronarsyndrom gut belegt. Neuere Untersuchungen...
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Article
Gender-related differences in left ventricular structural and functional responses to hypertension
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Chapter
Hartziekten
Hart- en vaatziekten zijn onverminderd de belangrijkste doodsoorzaak in Nederland. In 2001 overleden in Nederland in totaal meer dan 140.000 mensen. Van dit aantal overleden er 35% aan hart- en vaatziekten. Kw...
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Article
Haemodynamic patterns in ST-elevation myocardial infarction: incidence and correlates of elevated filling pressures
Objectives. We sought to study the incidence and clinical correlates of elevated filling pressures in ST-elevation myocardial infarction (STEMI) patients, without physical signs of heart failure and treated with ...
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Article
Hybrid approach for complex coronary artery and valve disease: a clinical follow-up study
For patients suffering from complex coronary artery disease (CAD) with or without concomitant valve disease, no evidence is available in the current guidelines to propose a predefined treatment regimen. We sou...
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Article
Clinical Trials Update from the European Society of Cardiology Congress in Vienna, 2007: PROSPECT, EVEREST, ARISE, ALOFT, FINESSE, Prague-8, CARESS in MI and ACUITY
The Clinical Trials described in this article were presented at the Hotline and Clinical Trial Update Sessions of the European Society of Cardiology Congress held in September 2007 in Vienna, Austria. The sess...
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Article
N-terminal pro B-type natriuretic peptide levels predict newly detected atrial fibrillation in a population-based cohort
Background B-type natriuretic peptide (BNP) is secreted from cardiomyocytes and may reflect haemodynamic abnormalities predisposing to atrial fibrillation (AF). We aimed to investigate whether N-terminal pro BNP ...
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Article
The post-infarction nurse practitioner project
Objectives To confirm the feasibility of nurse practitioner interventionin non-high-risk patients with recent myocardial infarction (MI).
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Article
Cardiac resynchronisation therapy and the role of optimal device utilisation
Despite established selection criteria, 30 to 40% of patients do not respond to cardiac resynchronisation therapy. By optimising programming of the device response to cardiac resynchronisation, therapy can be ...
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Article
Reduced regional myocardial perfusion reserve is associated with impaired contractile performance in idiopathic dilated cardiomyopathy
Background. In idiopathic dilated cardiomyopathy (IDC) an imbalance between myocardial oxygen consumption and supply has been postulated. Subclinical myocardial ischaemia may contribute to progressive deteriorati...
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Article
Neurohormonal profile of patients with heart failure and diabetes
Background. Neurohormonal activation is generally recognised to play an important role in the pathophysiology, prognosis and treatment of chronic heart failure (HF). While the number of patients with diabetes inc...
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Article
Apoptosis during CABG surgery with the use of cardiopulmonary bypass is prominent in ventricular but not in atrial myocardium
Objectives. We aimed to compare the rate of apoptosis after cardiopulmonary bypass (CPB) and cardioplegic arrest during coronary artery bypass grafting (CABG) surgery between atrial and ventricular tissue.
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Article
Open AccessDiastolic function measurements and diagnostic consequences: a comparison of pulsed wave- and color-coded tissue Doppler imaging
Tissue Doppler imaging (TDI) plays an important role in assessing diastolic function using echocardiography. However, two different methods [pulsed wave (PW-TDI) and color-coded (CC-TDI)] are currently used. W...