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Article
Association between sleep apnea and low bone mass in adults: a systematic review and meta-analysis
We performed a systematic review of the literature to assess the association between sleep apnea and bone metabolism diseases including osteoporosis in adult population. Results from clinical trials suggest th...
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Article
Metabolic consequences of snoring in adolescents and younger adults: a population study in Chile
To investigate the potential association between snoring and other symptoms indicative of sleep-disordered breathing and metabolic syndrome (MetS) in Hispanic adolescents and younger adults using a large popul...
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Article
Treatment with TUG891, a free fatty acid receptor 4 agonist, restores adipose tissue metabolic dysfunction following chronic sleep fragmentation in mice
Sleep fragmentation (SF), a frequent occurrence in multiple sleep and other diseases leads to increased food intake and insulin resistance via increased macrophage activation and inflammation in visceral white...
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Article
Erratum: Epigenomic profiling in visceral white adipose tissue of offspring of mice exposed to late gestational sleep fragmentation
Correction to: International Journal of Obesity accepted article preview 24 March 2015; doi:10.1038/ijo.2015.38 Since publication of this article the authors have noticed an error in the affiliations. Affiliat...
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Article
Epigenomic profiling in visceral white adipose tissue of offspring of mice exposed to late gestational sleep fragmentation
Sleep fragmentation during late gestation (LG-SF) is one of the major perturbations associated with sleep apnea and other sleep disorders during pregnancy. We have previously shown that LG-SF induces metabolic...
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Article
Effects of adenotonsillectomy on plasma inflammatory biomarkers in obese children with obstructive sleep apnea: A community-based study
Obesity and obstructive sleep apnea syndrome (OSA) are highly prevalent and frequently overlap** conditions in children that lead to systemic inflammation, the latter being implicated in the various end-orga...
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Article
Effect of resveratrol on visceral white adipose tissue inflammation and insulin sensitivity in a mouse model of sleep apnea
Sleep fragmentation (SF) increases food intake and the risk of obesity, and recruits macrophages to visceral white adipose tissue (VWAT) promoting tissue inflammation and insulin resistance. Administration of ...
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Article
Sleep fragmentation promotes NADPH oxidase 2-mediated adipose tissue inflammation leading to insulin resistance in mice
Short sleep has been implicated in higher risk of obesity in humans, and is associated with insulin resistance. However, the effects of fragmented sleep (SF) rather than curtailed sleep on glucose homeostasis ...
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Article
Effects of late gestational high-fat diet on body weight, metabolic regulation and adipokine expression in offspring
Gestational exposures such as dietary changes can alter offspring phenotype through epigenetic modifications and promote increased risk for specific diseases, such as metabolic syndrome. We hypothesized that h...
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Article
Neonatal intermittent hypoxia and hypertension
Obstructive apnea during sleep is accompanied by intermittent hypoxia (IH) leading to hypertension and other cardiovascular disturbances. A comparative evaluation of long-term effects of the neonatal IH on the...
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Article
Poster abstracts
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Article
Increased production of reactive oxygen species contributes to motor neuron death in a compression mouse model of spinal cord injury
Experimental laboratory investigation of the role and pathways of reactive oxygen species (ROS)-mediated motor neuron cell death in a mouse model of compression spinal cord injury.
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Article
The ventilatory response to hypoxia
We do not challenge the 'classic' theory of peripheral-chemoreceptor-mediated HVR. However, this offers no insight into the mediators of the time-domain components of HVR, such as ventilatory short-term potent...
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Article
Propofol Does Not Modify the Hemodynamic Status of Children with Intracardiac Shunts Undergoing Cardiac Catheterization
Immobility and cardiovascular stability are required for cardiac catheterization. Pediatric patients need a type of sedation that also allows spontaneous ventilation without supplemental oxygen. Propofol has b...
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Article
Potential Mechanisms of Failure in Sids As Revealed By Neural Imaging of Controls and Cchs Patients
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Article
Feeding: an alternative to sedation in children
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Article
L’électroencéphalogramme informatise en per-opératoire chez une patiente présentant une artérite de Takayasu
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Article
Haemophagocytosis in hereditary fructose intolerance: a diagnostic dilemma
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Article
Diffuse neonatal haemangiomatosis: Successful management with high dose corticosteroids
We report two cases of diffuse neonatal haemangiomatosis. The multiple cutaneous lesions were associated with massive hepatic involvement and congestive heart failure in one, while in the other laryngeal haema...
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Article
Arteriovenous haemangioma of the joint capsule of the knee in a child
We report a rare case of arteriovenous haemangioma of the knee joint in a girl. This treatable entity should be included in the differential diagnosis of nonspecific recurrent knee swelling or pain in children.