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Open AccessObservational multi-centre, prospective study to characterize novel pathogen-and host-related factors in hospitalized patients with lower respiratory tract infections and/or sepsis - the “TAILORED-Treatment” study
The emergence and spread of antibiotic resistant micro-organisms is a global concern, which is largely attributable to inaccurate prescribing of antibiotics to patients presenting with non-bacterial infections...
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Article
Non-fermentative Gram-negative rods bacteremia in children with cancer: a 14-year single-center experience
Data on non-fermentative Gram-negative rods (NFGNR) bacteremia in children with malignancies are limited. The aim of this study was to present clinical picture, antimicrobial susceptibility pattern, risk facto...
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Article
Colistin is relatively safe in hematological malignancies and hematopoietic stem cell transplantation patients
Colistin is increasingly used as the last-resort treatment option against infections caused by multidrug-resistant (MDR) Gram-negative pathogens, but its nephrotoxicity is of concern, especially in severely il...
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Bacterial infection prevention after hematopoietic cell transplantation
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Article
Management of HSV, VZV and EBV infections in patients with hematological malignancies and after SCT: guidelines from the Second European Conference on Infections in Leukemia
These guidelines on the management of HSV, VZV and EBV infection in patients with hematological malignancies and after SCT were prepared by the European Conference on Infections in Leukemia following a predefi...
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Article
Management of CMV, HHV-6, HHV-7 and Kaposi-sarcoma herpesvirus (HHV-8) infections in patients with hematological malignancies and after SCT
These recommendations were prepared by the European Conference on Infections in Leukaemia following a predefined methodology. Literature searches were made to identify studies pertinent to management of CMV, H...
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Article
Vaccination of stem cell transplant recipients: recommendations of the Infectious Diseases Working Party of the EBMT
Over the last 25 years, the numbers of hematopoietic stem cell transplant (SCT) patients have increased rapidly. Infections have been major obstacles for successful transplantation. Thus, infection prevention ...
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Management of CMV infections: recommendations from the infectious diseases working party of the EBMT
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Article
Severe Hypothermia Induced by Dipyrone Overdose
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Unusual cytomegalovirus complications after autologous stem cell transplantation for large B cell lymphoma: massive gastrointestinal hemorrhage followed by a communicating hydrocephalus
Unusual cytomegalovirus (CMV)-related complications were seen after autologous stem cell transplantation (SCT) in a 50-year-old patient with diffuse large B cell lymphoma. One month after SCT, the patient deve...
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Article
Immune reconstitution following allogeneic stem cell transplantation in recipients conditioned by low intensity vs myeloablative regimen
We have investigated the immune status of patients with hematologic malignancies treated with a low intensity conditioning in preparation for allogeneic stem cell transplantation. Conditioning consisted of flu...
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Article
Atrioventricular Block in a Toxic Child: Do Not Forget Diphtheria
We describe a 4.5-year-old girl who presented with severe febrile throat infection and who, after a few days, developed ventricular tachycardia followed by atrioventricular block. Although a pacemaker was ins...
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Article
Cytomegalovirus pneumonia prior to engraftment following T-cell depleted bone marrow transplantation
CMV pneumonia is a frequent complication of allogeneic bone marrow transplantation (BMT). It usually appears 23 months following transplantation and is associated with a high mortality rate. The incidence of C...
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Article
Parenteral-Oral Switch in the Management of Paediatric Pneumonia
In phase I of a 2-phase study, 56 evaluable children (0.8 to 5 years) with lobar or segmental pneumonia received intravenous or intramuscular ceftriaxone 50 mg/kg/day for 2 days followed by oral cefetamet pivo...
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Factors Affecting Normal and Malignant B Lymphocyte Precursors
There is a large scale daily production of B lymphocytes within bone marrow of mammals, however until recently, little has been known about cellular interactions or humoral factors which normally regulate this...