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  1. No Access

    Article

    Role of cannabinoid receptors in regulation of cardiac tolerance to ischemia and reperfusion

    Coronary artery occlusion (45 min) and reperfusion (2 h) were modeled in vivo in anesthetized artificially ventilated Wistar rats. Total ischemia (45 min) and reperfusion (30 min) of the isolated rat heart wer...

    O. V. Lasukova, L. N. Maslov, S. Yu. Ermakov, D. Crawford, F. Barth… in Biology Bulletin (2008)

  2. No Access

    Article

    Activation of k1-opioid receptor as a method for prevention of ischemic and reperfusion arrhythmias: Role of protein kinase C and KATP channels

    Intravenous pretreatment with κ-opioid receptor antagonist (−)-U-50,488 (1 mg/kg) improved heart resistance to the arrhythmogenic effect of coronary occlusion and reperfusion. Selective κ1-opioid receptor antagon...

    A. Yu. Lishmanov, L. N. Maslov… in Bulletin of Experimental Biology and Medic… (2007)

  3. No Access

    Article

    Significance of cardiac cannabinoid receptors in regulation of cardiac rhythm, myocardial contractility, and electrophysiologic processes in heart

    Intravenous administration of cannabinoid (CB) receptor agonists (HU-210, 0.1 mg/kg; ACPA, 0.125 mg/kg; methanandamide, 2.5 mg/kg; and anandamide, 2.5 mg/kg) induced bradycardia in chloralose-anesthetized rats...

    A. V. Krylatov, L. N. Maslov, S. Yu. Ermakov, O. V. Lasukova… in Biology Bulletin (2007)

  4. No Access

    Article

    Negative chronotropic effect of cannabinoids and their water-soluble emulsion is related to activation of cardiac CB1 receptors

    Intravenous injection of cannabinoids dissolved in cremophore EL:ethanol:NaCl mixture and water-soluble emulsion of the same cannabinoids caused identical negative chronotropic effects in chloralose-narcotized...

    A. V. Krylatov, L. N. Maslov, S. Yu. Ermakov… in Bulletin of Experimental Biology and Medic… (2006)