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Article
Surface damage of single-crystal silicon abraded in ethanol and deionized water
Semiconductor grade, single-crystal silicon wafers of (1 0 0) p-type were abraded by a single-point, slow speed (2.3 cm sec−1) 90° pyramid diamond in ethanol and deionized water. The scratching was carried out in...
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Effects of Metallic Impurities upon thin Gate Oxide Integrity and Related Bulk Properties in CZ Si
In this study, we investigated effects of various well-known metallic impurities such as Fe, Cu, and Al (contaminated by a spin coating method with concentration levels ranged from 1 × 1010 to 1 × 1010 atoms/cm2)...
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Article
Risk-Stratified Approach to Hybrid Transcatheter–Surgical Palliation of Hypoplastic Left Heart Syndrome
We prospectively employed a risk-stratified approach to first-stage palliation of hypoplastic left heart syndrome. High-risk features included severe tricuspid insufficiency, severe right ventricular dysfuncti...
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Article
N-acetylphytosphingosine-induced apoptosis of Jurkat cells is mediated by the conformational change in Bak
N-acetylphytosphingosine (NAPS), a sphingolipid derivative, is one of the well-known signal molecules that mediates various cellular functions, including cell growth, differentiation, and apoptosis. In this st...
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Article
Traumatic Ascending Aortopulmonary Window Following Pulmonary Artery Stent Dilatation: Therapy with Aortic Endovascular Stent Graft
Endovascular stent grafts have become an established therapy in adults for descending thoracic aortic disease. We report a case of a 13-year-old boy with a hemodynamically significant traumatic aortopulmonary ...
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Article
Effect of attrition milling on dispersion of onion like carbon in aqueous medium
Nanodiamond powders, synthesized by the detonation of explosives, can be transformed into onion like carbon (OLC) by means of thermal treatment in inert environments. OLC aggregates could not be reduced to nan...
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Article
TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial–mesenchymal transition
TMPRSS4 is a novel type II transmembrane serine protease found at the cell surface that is highly expressed in pancreatic, colon and gastric cancer tissues. However, the biological functions of TMPRSS4 in canc...
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Article
Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G1–S transition
The tumor suppressor RASSF1A is inactivated in many human cancers and is implicated in regulation of microtubule stability, cell cycle progression and apoptosis. However, the precise mechanisms of RASSF1A acti...
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Article
PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression
Pancreatic cancer is characterized by early metastatic spread, but the process of tumor cell dissemination is largely unknown. In this study we show that the soluble protein pancreatic adenocarcinoma upregulat...
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Article
Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation
Pancreatic adenocarcinoma upregulated factor (PAUF) is overproduced in certain types of cancer. However, little is known of the tumorigenic function of PAUF. In this study, we report the X-ray crystal structur...
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Article
Comprehensive study of the surface morphology evolution induced by thermal annealing in single-crystalline ZnO Films and ZnO bulks
We report on the evolution of the surface morphology induced by thermal annealing in N2 ambient over a wide temperature range of 500–1200 °C in single-crystalline ZnO films and ZnO bulks. The surface morphology i...
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Article
Open AccessRAF kinase inhibitor-independent constitutive activation of Yes-associated protein 1 promotes tumor progression in thyroid cancer
The transcription coactivator Yes-associated protein 1 (YAP1) is regulated by the Hippo tumor suppressor pathway. However, the role of YAP1 in thyroid cancer, which is frequently associated with the BRAFV600E mut...
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Article
Open AccessLigand-activated peroxisome proliferator-activated receptor-δ and -γ inhibit lipopolysaccharide-primed release of high mobility group box 1 through upregulation of SIRT1
Peroxisome proliferator-activated receptors (PPARs) inhibit lipopolysaccharide (LPS)-primed release of high mobility group box 1 (HMGB1), a late proinflammatory mediator, but the underlying molecular mechanism...
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Article
Open AccessModulation of dendritic cell function by the radiation-mediated secretory protein γ-synuclein
Recently, γ-synuclein (SNCG), which is also known as breast cancer-specific gene-1, has been demonstrated to be an adverse and aggressive marker in breast cancer. In our previous study, SNCG was significantly upr...
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Article
Open AccessRadiation-induced gamma-synuclein in regards to DC function