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    Article

    Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes

    In addition to their cytoprotective role in stressful conditions, heat shock proteins (HSPs) are involved in specific differentiation pathways, for example, we have identified a role for HSP90 in macrophage di...

    G Jego, D Lanneau, A De Thonel, K Berthenet, A Hazoumé, N Droin, A Hamman… in Leukemia (2014)

  2. Article

    Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level

    TNF-related apoptosis-inducing ligand or Apo2L (Apo2L/TRAIL) is a promising anti-cancer drug owing to its ability to trigger apoptosis by binding to TRAIL-R1 or TRAIL-R2, two membrane-bound receptors that are ...

    A Morizot, D Mérino, N Lalaoui, G Jacquemin, V Granci… in Cell Death & Differentiation (2011)

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  3. Article

    Interaction of heat-shock protein 90β isoform (HSP90β) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation

    Members of the inhibitor of apoptosis protein (IAP) family have demonstrated functions in cell death, cell signalling, cell migration and mitosis. Several of them are E3 enzymes in the ubiquitination of protei...

    C Didelot, D Lanneau, M Brunet, A Bouchot, J Cartier… in Cell Death & Differentiation (2008)

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