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Open AccessExercise training as a novel primary treatment for localised prostate cancer: a multi-site randomised controlled phase II study
Alternative management strategies for localised prostate cancer are required to reduce morbidity and overtreatment. The aim of this study was to evaluate the feasibility, safety and acceptability of exercise t...
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Article
Open AccessResponse to comment on ‘Interventions to improve exercise behaviour in sedentary people living with and beyond cancer: a systematic review’
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Article
Open AccessInterventions to improve exercise behaviour in sedentary people living with and beyond cancer: a systematic review
To systematically review the effects of interventions to improve exercise behaviour in sedentary people living with and beyond cancer.
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Article
Open AccessNuclear targeting of dystroglycan promotes the expression of androgen regulated transcription factors in prostate cancer
Dystroglycan is frequently lost in adenocarcinoma, but the mechanisms and consequences are poorly understood. We report an analysis of β-dystroglycan in prostate cancer in human tissue samples and in LNCaP cells
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Open AccessReply: Endocrine therapy in prostate cancer: time for reappraisal of risks, benefits and cost-effectiveness?
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Article
Open AccessCompeting mortality in patients diagnosed with bladder cancer: evidence of undertreatment in the elderly and female patients
Bladder cancer (BC) predominantly affects the elderly and is often the cause of death among patients with muscle-invasive disease. Clinicians lack quantitative estimates of competing mortality risks when consi...
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Article
Open AccessEndocrine therapy in prostate cancer: time for reappraisal of risks, benefits and cost-effectiveness?
In the 70 years following the first description of the benefits of surgical castration, despite advances in medical therapy e.g. cabazitaxel, enzalutamide, abiraterone, androgen deprivation therapy (ADT) remai...
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Open AccessAn evaluation of urinary microRNA reveals a high sensitivity for bladder cancer
Urinary biomarkers are needed to improve the care and reduce the cost of managing bladder cancer. Current biomarkers struggle to identify both high and low-grade cancers due to differing molecular pathways. Ch...
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Article
Open AccessSuitability of PSA-detected localised prostate cancers for focal therapy: experience from the ProtecT study
Contemporary screening for prostate cancer frequently identifies small volume, low-grade lesions. Some clinicians have advocated focal prostatic ablation as an alternative to more aggressive interventions to m...
