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  1. Article

    Open Access

    Vitamin D receptor gene polymorphisms are associated with breast cancer risk in a UK Caucasian population

    There is increasing evidence that vitamin D can protect against breast cancer. The actions of vitamin D are mediated via the vitamin D receptor (VDR). We have investigated whether polymorphisms in the VDR gene...

    D Bretherton-Watt, R Given-Wilson, J L Mansi, V Thomas in British Journal of Cancer (2001)

  2. Article

    Failure to establish islet amyloid polypeptide (amylin) as a circulating beta cell inhibiting hormone in man

    The presence of islet amyloid polypeptide in amyloid within pancreatic islet cells in Type 2 (non-insulin-dependent) diabetes, and its reported inhibition of glucose uptake by skeletal muscle in vitro, has pro...

    D. Bretherton-Watt, S. G. Gilbey, M. A. Ghatei, J. Beacham in Diabetologia (1990)

  3. Article

    Altered islet amyloid polypeptide (amylin) gene expression in rat models of diabetes

    The response of the islet amyloid polypeptide gene to chronic dexamethasone treatment in adult rats was investigated. After 12 daily injections, rats were severely underweight and fasting blood glucose levels ...

    D. Bretherton-Watt, M. A. Ghatei, S. R. Bloom, H. Jamal, G. J. M. Ferrier in Diabetologia (1989)