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Article
Open AccessVitamin D receptor gene polymorphisms are associated with breast cancer risk in a UK Caucasian population
There is increasing evidence that vitamin D can protect against breast cancer. The actions of vitamin D are mediated via the vitamin D receptor (VDR). We have investigated whether polymorphisms in the VDR gene...
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Article
Failure to establish islet amyloid polypeptide (amylin) as a circulating beta cell inhibiting hormone in man
The presence of islet amyloid polypeptide in amyloid within pancreatic islet cells in Type 2 (non-insulin-dependent) diabetes, and its reported inhibition of glucose uptake by skeletal muscle in vitro, has pro...
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Article
Altered islet amyloid polypeptide (amylin) gene expression in rat models of diabetes
The response of the islet amyloid polypeptide gene to chronic dexamethasone treatment in adult rats was investigated. After 12 daily injections, rats were severely underweight and fasting blood glucose levels ...