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    Article

    Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence

    SOX5 is a member of the high-mobility group superfamily of architectural non-histone proteins involved in gene regulation and maintenance of chromatin structure in a wide variety of developmental processes. So...

    E Tchougounova, Y Jiang, D Bråsäter, N Lindberg, M Kastemar, A Asplund in Oncogene (2009)

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    Article

    Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma

    In a subset of gliomas, the platelet-derived growth factor (PDGF) signaling pathway is perturbed. This is usually an early event occurring in low-grade tumors. In high-grade gliomas, the subsequent loss of the IN...

    E Tchougounova, M Kastemar, D Bråsäter, E C Holland, B Westermark, L Uhrbom in Oncogene (2007)