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Open AccessPredictive value of NoSAS questionnaire combined with the modified Mallampati grade for hypoxemia during routine sedation for gastrointestinal endoscopy
The incidence of hypoxemia during painless gastrointestinal endoscopy remains a matter of concem. To date, there is no recognized simple method to predict hypoxemia in digestive endoscopic anesthesia. The NoSA...
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Open AccessLateral septum-lateral hypothalamus circuit dysfunction in comorbid pain and anxiety
Pain and anxiety comorbidities are a common health problem, but the neural mechanisms underlying comorbidity remain unclear. We propose that comorbidity implies that similar brain regions and neural circuits, ...
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Article
Open AccessThe soluble epoxide hydrolase inhibitor TPPU improves comorbidity of chronic pain and depression via the AHR and TSPO signaling
Patients suffering from chronic pain often also exhibit depression symptoms. Soluble epoxide hydrolase (sEH) inhibitors can decrease blood levels of inflammatory cytokines. However, whether inhibiting sEH sign...
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Article
Open AccessEffect of differences in extubation timing on postoperative pneumonia following meningioma resection: a retrospective cohort study
This study was designed to examine extubation time and to determine its association with postoperative pneumonia (POP) after meningioma resection.
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Article
Open AccessThe effects of fentanyl, oxycodone, and butorphanol on gastrointestinal function in patients undergoing laparoscopic hysterectomy: a prospective, double-blind, randomized controlled trial
Perioperative opioid use is associated with postoperative bowel dysfunction, which causes longer hospital stay and higher healthcare costs. This study aimed to investigate the effect of the equivalent doses of...
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Article
Open AccessPredominant role of gut-vagus-brain neuronal pathway in postoperative nausea and vomiting: evidence from an observational cohort study
Postoperative nausea and vomiting (PONV) as a clinically most common postoperative complication requires multimodal antiemetic medications targeting at a wide range of neurotransmitter pathways. Lacking of neu...
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Article
Open AccessmiR-98-5p plays a critical role in depression and antidepressant effect of ketamine
Ketamine has been demonstrated to be a rapid-onset and long-lasting antidepressant, but its underlying molecular mechanisms remain unclear. Recent studies have emerged microRNAs as important modulators for dep...
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Article
Open AccessEmergence agitation after intraoperative neurolytic celiac plexus block with alcohol: a case report
Emergence agitation after general anesthesia may cause several undesirable events in the clinic during patient anesthesia recovery, and acute alcohol intoxication, while rare in surgery, is one of the risk fac...
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Article
Author Correction: Aqueous Li-ion battery enabled by halogen conversion–intercalation chemistry in graphite
In Fig. 3e of this Letter, the labels “Br-Cl1” and “Br-Cl2” should read “Br-Br1” and “Br-Br2”, respectively. In the Methods section ‘Preparation of electrodes’, the phrase “anhydrous LiBr/LiCl was replaced by ...
