Drug Targeting
Strategies, Principles, and Applications
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Open AccessExploring epipelic diatom species composition across wetlands conductivity gradients in southern Spain
The objective of this study was to explore the environmental factors having the greatest influence on the distribution and abundance of epipelic diatom species in different wetlands in southern Spain. We previ...
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Article
Open AccessEvaluation of the inter and intraobserver reproducibility of the “defect coverage index method”, a new computed tomography assessment method of sagittal graft positioning in arthroscopic bone block procedures
To assess the reproducibility of a new 2-dimensional computed tomography (CT) method of assessing graft positioning in arthroscopic bone block procedure.
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Article
Open AccessManagement of off-track Hill-Sachs lesions in anterior glenohumeral instability
Bone loss has been identified as a risk factor for recurrent shoulder dislocations or failure after soft tissue repair. Although the range for “critical” bone loss is yet to be determined, glenoid and humeral ...
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Article
Open AccessVariability of diatom community composition and structure in mountain streams
Small rivers support high levels of biodiversity, being especially sensitive to the effects of global change. Temporal records of community composition in minimally impaired streams can be used to explore tren...
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Diatom Species that Characterize Saline Ponds (Southern Spain) with the Description of a New Navicula Species
The southern Iberian Peninsula has a high number of saline ponds where electric conductivity (EC) is an important factor that directly affects the distribution and abundance of aquatic organisms. Environmental...
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Ecological assessment of Portuguese reservoirs based on littoral epilithic diatoms
The objective of this study was to evaluate whether biological methods based on epilithic littoral diatoms are a valuable complement to other biological elements for the assessment of the ecological potential ...
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Article
Fever and deep venous thrombosis. Findings from the RIETE registry
Fever is a presenting sign in some patients with acute deep venous thrombosis (DVT), but its influence on outcome has not been thoroughly investigated. RIETE is an ongoing, international, observational registr...
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A multimetric diatom index to assess the ecological status of coastal Galician rivers (NW Spain)
There are many rivers in northwest Spain as a consequence of the mountainous landscape and the granitic geology subjected to Atlantic influences. Water and epilithic diatoms samples were collected at 72 sites ...
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Article
A comparison of national approaches to setting ecological status boundaries in phytobenthos assessment for the European Water Framework Directive: results of an intercalibration exercise
The European Union (EU)’s Water Framework Directive (WFD) requires that all Member States participate in intercalibration exercises in order to ensure that ecological status concepts and assessment levels are ...
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Minimizing Labor Requirements in a Periodic Vehicle Loading Problem
In this paper, we address a logistics problem that a manufacturer of auto parts in the north of Spain described to the authors. The manufacturer stores products in its warehouse until customers retrieve them. ...
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Book
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Chapter
Partitioning of Polyethylene Glycol(PEG)-Protein Conjugates in PEG/Dextran Aqueous Two-Phase Systems
Covalent attachment of polyethylene glycol (PEG) to proteins produces an increase in their partition coefficient (K) in PEG/dextran aqueous two-phase systems. At least for bovine serum albumin (BSA) and granul...
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Chapter
Pegylation of Membrane Surfaces
Polyethylene glycol (PEG) is a long chain, relatively inert and non-toxic water-soluble polymer. PEG-modification of clinically useful proteins makes dramatic improvements in their biological properties by inc...
