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  1. No Access

    Article

    Sex-by-formulation interaction in bioequivalence trials with transdermal patches

    The existence of a sex-by-formulation interaction in bioequivalence studies implies that the bioequivalence results (i.e., the test/reference ratio of the pharmacokinetic parameters) obtained in one sex are no...

    Esperanza González-Rojano, Julio Marcotegui… in European Journal of Clinical Pharmacology (2019)

  2. No Access

    Article

    Bioequivalence between generic tacrolimus products marketed in Spain by adjusted indirect comparison

    The objective of the study was to investigate the relative bioavailability between the generic tacrolimus products that are presently authorized in Spain by adjusted indirect comparison. This was based on demo...

    Marta Herranz, Susana Morales-Alcelay… in European Journal of Clinical Pharmacology (2013)

  3. No Access

    Article

    Differences in lercanidipine systemic exposure when administered according to labelling: in fasting state and 15 minutes before food intake

    The aim of this study was to compare the systemic exposure of lercanidipine (Zanidip) after oral administration in the fasted state and 15 min before food intake (meals) to investigate if the recommendations i...

    Covadonga Álvarez, Estrella Gómez, Marta Simón… in European Journal of Clinical Pharmacology (2012)