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  1. Article

    Open Access

    Protein supplementation during an energy-restricted diet induces visceral fat loss and gut microbiota amino acid metabolism activation: a randomized trial

    Interactions between diet and gut microbiota are critical regulators of energy metabolism. The effects of fibre intake have been deeply studied but little is known about the impact of proteins. Here, we invest...

    Pierre Bel Lassen, Eugeni Belda, Edi Prifti, Maria Carlota Dao in Scientific Reports (2021)

  2. No Access

    Article

    Developmental mechanisms of stripe patterns in rodents

    Mammalian colour patterns are among the most recognizable characteristics found in nature and can have a profound impact on fitness. However, little is known about the mechanisms underlying the formation and s...

    Ricardo Mallarino, Corneliu Henegar, Mercedes Mirasierra, Marie Manceau in Nature (2016)

  3. No Access

    Article

    Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses

    Leif Andersson, Gregory Barsh and colleagues show that Dun camouflage color in horses is due to TBX3 expression in hair follicles, which causes asymmetric distribution of hair follicle melanocytes and reduced ...

    Freyja Imsland, Kelly McGowan, Carl-Johan Rubin, Corneliu Henegar in Nature Genetics (2016)

  4. No Access

    Article

    Dynamic Relations Between Sedentary Behavior, Physical Activity, and Body Composition After Bariatric Surgery

    Physical activity has been shown to increase following obesity surgery; however, changes in sedentary behavior in this setting are not known. Our aim was to describe changes in both physical activity and seden...

    Camille Vatier, Corneliu Henegar, Cécile Ciangura in Obesity Surgery (2012)

  5. Article

    Open Access

    Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

    Investigations performed in mice and humans have acknowledged obesity as a low-grade inflammatory disease. Several molecular mechanisms have been convincingly shown to be involved in activating inflammatory pr...

    Corneliu Henegar, Joan Tordjman, Vincent Achard, Danièle Lacasa in Genome Biology (2008)

  6. Chapter and Conference Paper

    Unsupervised Multiple-Instance Learning for Functional Profiling of Genomic Data

    Multiple-instance learning (MIL) is a popular concept among the AI community to support supervised learning applications in situations where only incomplete knowledge is available. We propose an original refor...

    Corneliu Henegar, Karine Clément, Jean-Daniel Zucker in Machine Learning: ECML 2006 (2006)