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Article
Open AccessProtein supplementation during an energy-restricted diet induces visceral fat loss and gut microbiota amino acid metabolism activation: a randomized trial
Interactions between diet and gut microbiota are critical regulators of energy metabolism. The effects of fibre intake have been deeply studied but little is known about the impact of proteins. Here, we invest...
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Article
Developmental mechanisms of stripe patterns in rodents
Mammalian colour patterns are among the most recognizable characteristics found in nature and can have a profound impact on fitness. However, little is known about the mechanisms underlying the formation and s...
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Article
Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses
Leif Andersson, Gregory Barsh and colleagues show that Dun camouflage color in horses is due to TBX3 expression in hair follicles, which causes asymmetric distribution of hair follicle melanocytes and reduced ...
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Article
Dynamic Relations Between Sedentary Behavior, Physical Activity, and Body Composition After Bariatric Surgery
Physical activity has been shown to increase following obesity surgery; however, changes in sedentary behavior in this setting are not known. Our aim was to describe changes in both physical activity and seden...
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Article
Open AccessAdipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity
Investigations performed in mice and humans have acknowledged obesity as a low-grade inflammatory disease. Several molecular mechanisms have been convincingly shown to be involved in activating inflammatory pr...
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Chapter and Conference Paper
Unsupervised Multiple-Instance Learning for Functional Profiling of Genomic Data
Multiple-instance learning (MIL) is a popular concept among the AI community to support supervised learning applications in situations where only incomplete knowledge is available. We propose an original refor...