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    An endogenous opioid circuit determines state-dependent reward consumption

    µ-Opioid peptide receptor (MOPR) stimulation alters respiration, analgesia and reward behaviour, and can induce substance abuse and overdose1–3. Despite its evident importance, the endogenous mechanisms for MOPR ...

    Daniel C. Castro, Corinna S. Oswell, Eric T. Zhang, Christian E. Pedersen… in Nature (2021)