6 Result(s)
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Coraline Radermecker
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Article
Open AccessMafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation
Resident tissue macrophages (RTMs) are differentiated immune cells that populate distinct niches and exert important tissue-supportive functions. RTM maintenance is thought to rely either on differentiation fr...
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Protocol
Methods to Detect Neutrophil Extracellular Traps in Asthma
have the ability to regulate many aspects of asthma pathology. NETs can be detected either in bronchoalveolar fluids (BALF) or in lung biopsies. Here, we describe methods to quantify NETs in BALF, namely ...
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Article
Locally instructed CXCR4hi neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps
Low exposure to microbial products, respiratory viral infections and air pollution are major risk factors for allergic asthma, yet the mechanistic links between such conditions and host susceptibility to type ...
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Article
Open AccessNon-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
Resident tissue macrophages (RTM) can fulfill various tasks during development, homeostasis, inflammation and repair. In the lung, non-alveolar RTM, called interstitial macrophages (IM), importantly contribute...
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Article
Correction: Corrigendum: Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation
Nat. Med. 23, 681–691 (2017); published online 1 May 2017; corrected after print 12 July 2017 In the version of this article initially published, Dr. Nathan W Bartlett was inadvertently omitted from the author...
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Article
Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation
Targeting NETosis alleviates type-2 immunopathology induced by rhinovirus infection in a mouse model of airway hypersensitivity, and correlative data suggest that a similar mechanism may operate in human rhino...
