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    Article

    Ca2+-mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and Bak

    The ability of mitochondria to buffer a rapid rise in cytosolic Ca2+ is a hallmark of proper cell homeostasis. Here, we employed m-3M3FBS, a putative phospholipase C (PLC) agonist, to explore the relationships be...

    Giovanni Quarato, Fabien Llambi, Cliff S. Guy, Jaeki Min… in Cell Death & Differentiation (2022)

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    Article

    Metabolic maintenance of cell asymmetry following division in activated T lymphocytes

    The asymmetric distribution of mTORC1 and c-Myc in the first division of daughter cells of activated CD8 T cells affects the proliferation, metabolism and differentiation potential of their progeny.

    Katherine C. Verbist, Cliff S. Guy, Sandra Milasta, Swantje Liedmann… in Nature (2016)