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Article
Open AccessSARS-CoV-2 transmission in teenagers and young adults in Fútbol Club Barcelona’s Multidisciplinary Sports Training Academy
Most studies, aimed at determining the incidence and transmission of SARS-CoV-2 in children and teenagers, have been developed in school settings. Our study conducted surveillance and inferred attack rates foc...
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Article
Open AccessDual latent tuberculosis screening with tuberculin skin tests and QuantiFERON-TB assays before TNF-α inhibitor initiation in children in Spain
Tumor-necrosis-factor-α inhibitors (anti-TNF-α) are associated with an increased risk of tuberculosis (TB) disease, primarily due to reactivation of latent TB infection (LTBI). We assessed the performance of p...
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Article
Open AccessHost, technical, and environmental factors affecting QuantiFERON-TB Gold In-Tube performance in children below 5 years of age
Interferon-gamma release assays performance can be impaired by host-related, technical and environmental factors, but data in young children are limited. We performed a cross-sectional study of children < 5 ye...
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Article
Open AccessAntibody conversion rates to SARS-CoV-2 in saliva from children attending summer schools in Barcelona, Spain
Surveillance tools to estimate viral transmission dynamics in young populations are essential to guide recommendations for school opening and management during viral epidemics. Ideally, sensitive techniques ar...
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Article
Open AccessSevere Autoinflammatory Manifestations and Antibody Deficiency Due to Novel Hypermorphic PLCG2 Mutations
Autoinflammatory diseases (AIDs) were first described as clinical disorders characterized by recurrent episodes of seemingly unprovoked sterile inflammation. In the past few years, the identification of novel ...
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Article
Use of procalcitonin in the diagnosis of tuberculosis in infants and preschool children
Normal procalcitonin (PCT) levels have been reported in adult pulmonary tuberculosis (TB) but have not been previously investigated in children. We aimed to assess PCT levels at diagnosis of TB in young childr...
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Article
Influence of new antiretrovirals on hematological toxicity in HIV-exposed uninfected infants
Maternal combined antiretroviral therapy (cART) successfully prevents HIV mother-to-child transmission but also causes hematological toxicity in the HIV-exposed uninfected (HEU) infant. We performed a single-c...
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Article
Open AccessTuberculosis in pediatric patients treated with anti-TNFα drugs: a cohort study
Adult patients receiving anti-TNFα drugs are at increased risk of tuberculosis (TB), but studies in pediatric populations are limited, and the best strategy for latent tuberculosis infection (LTBI) screening i...
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Article
The role of albuminuria in the follow-up of HIV-infected pediatric patients
In HIV-infected adults, elevated albumin has been associated with increased inflammatory activity, HIV-related nephropathy, and type 2 diabetes. Data on albuminuria in HIV-infected children are very scarce, an...
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Article
Correction: Corrigendum: B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen
Nat. Immunol. 13, 170–180 (2012); published online 25 December 2011; corrected after print 12 July 2013 In the version of this article initially published, the second affiliation for Stephanie C. Ganal is miss...
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Article
Open AccessA new tool for the paediatric HIV research: general data from the Cohort of the Spanish Paediatric HIV Network (CoRISpe)
There are approximately from 1,100 to 1,200 HIV-infected children in a follow-up in Spain. In 2008 an open, multicentral, retrospective and prospective Cohort of the Spanish Paediatric HIV Network (CoRISpe) wa...
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Article
B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen
Follicular T cells provide help to B cells to elicit antibody responses. Cerutti and colleagues show that neutrophils provide help to marginal-zone B cells that produce T cell–independent antibodies.
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Article
The prevalence of GB virus C/hepatitis G virus RNA among healthy and HCV-infected Catalan children
GB virus C (GBV-C) is a blood-borne flavivirus. The prevalence of GBV-C viremia among healthy adults is 0.5% to 4% and, to date, no disease has been definitely associated with GBV-C infection. We conducted a c...
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Article
Mother-to-child transmission of hepatitis C virus infection in Barcelona, Spain: a prospective study
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Chapter and Conference Paper
Mother-to-Infant Transmission of Hepatitis C Virus—A Prospective Study
Some studies and case reports suggest that mother-to-infant transmission of hepatitis C virus (HCV) is uncommon. However, the real extent of vertical and perinatal transmission of HCV is unknown. We prospectiv...
