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  1. Article

    Electrophysiological mechanisms of sophocarpine as a potential antiarrhythmic agent

    To examine the electrophysiological effects of sophocarpine on action potentials (AP) and ionic currents of cardiac myocytes and to compare some of these effects with those of amiodarone.

    Zhi-fang Yang, Ci-zhen Li, Wei Wang, Ying-min Chen in Acta Pharmacologica Sinica (2011)

  2. Article

    Beta-receptor activation increases sodium current in guinea pig heart

    To study the influence of β-receptor activation on sodium channel current and the physiological significance of increased sodium current with regard to the increased cardiac output caused by sympathetic excita...

    Hong-wei Wang, Zhi-fang Yang, Yin Zhang, Jian-min Yang in Acta Pharmacologica Sinica (2009)

  3. Article

    Possible arrhythmiogenic mechanism produced by ibuprofen

    The aim of the present study was to investigate the electrophysiological effect of ibuprofen on the cardiac action potentials (AP) and electrocardiograms (ECG), and to identify its arrhythmiogenic mechanism.

    Zhi-fang Yang, Hong-wei Wang, Yan-qian Zheng, Yin Zhang in Acta Pharmacologica Sinica (2008)

  4. Article

    Electrophysiological effect of fluoxetine on Xenopus oocytes heterologously expressing human serotonin transporter

    To investigate the electrophysiological effect of fluoxetine on serotonin transporter.

    Hong-wei Wang, Ci-zhen Li, Zhi-fang Yang, Yan-qian Zheng in Acta Pharmacologica Sinica (2006)