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  1. No Access

    Article

    Open versus laparoscopic Hartmann’s procedure: a systematic review and meta-analysis

    Hartmann’s procedure is traditionally performed in emergency situations where single-step procedures with immediate anastomosis may be unsafe. However, it can be associated with significant morbidity and low c...

    Yingjia Zhang, Chunxi Liu… in International Journal of Colorectal Disease (2022)

  2. Article

    Open Access

    Irinotecan/scFv co-loaded liposomes coaction on tumor cells and CAFs for enhanced colorectal cancer therapy

    Cancer-associated fibroblasts (CAFs), as an important component of stroma, not only supply the “soils” to promote tumor invasion and metastasis, but also form a physical barrier to hinder the penetration of th...

    Zhaohuan Li, Chunxi Liu, Chenglei Li, Fangqing Wang… in Journal of Nanobiotechnology (2021)

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  3. Article

    Open Access

    SOX9 is a dose-dependent metastatic fate determinant in melanoma

    In this research, we aimed to resolve contradictory results whether SOX9 plays a positive or negative role in melanoma progression and determine whether SOX9 and its closely related member SOX10 share the same...

    **ntao Yang, Rui Liang, Chunxi Liu… in Journal of Experimental & Clinical Cancer … (2019)

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  4. No Access

    Article

    miR-338 suppresses the growth and metastasis of OSCC cells by targeting NRP1

    microRNAs (miRNAs) are small non-coding RNAs that have been suggested to play an essential role in tumorigenesis. Reduced expression of miR-338 has been reported in several types of cancers; however, the role ...

    Chunxi Liu, Zhiyu Wang, Yi Wang, Wuwei Gu in Molecular and Cellular Biochemistry (2015)

  5. No Access

    Article

    Web video thumbnail recommendation with content-aware analysis and query-sensitive matching

    In this paper, a unified and adaptive web video thumbnail recommendation framework is proposed, which recommends thumbnails both for video owners and browsers on the basis of image quality assessment, image ac...

    Weigang Zhang, Chunxi Liu, Zhenjun Wang, Guorong Li… in Multimedia Tools and Applications (2014)

  6. No Access

    Article

    Tumor-Specific Delivery and Therapy by Double-Targeted DTX-CMCS-PEG-NGR Conjugates

    To synthesize and evaluate the antitumor efficacy of double-targeted docetaxel (DTX)-carboxymethyl chitosan (CMCS)-PEG-NGR (DTX-CPN) conjugates that could target to CD13 over-expressed tumor neovascular endoth...

    Fengxi Liu, Min Li, Chunxi Liu, Yongjun Liu, Yanchao Liang… in Pharmaceutical Research (2014)

  7. Chapter and Conference Paper

    Research and Application of Variable Rate Fertilizer Applicator System Based on a DC Motor

    With the aim to simplify the electrical component structure of the present variable rate fertilizer applicator system, a kind of variable rate fertilizer applicator control system was developed. It is based on...

    Honglei Jia, **anzhen Feng, Jiangtao Qi… in Computer and Computing Technologies in Agr… (2014)

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  8. No Access

    Chapter and Conference Paper

    Coarse-to-Fine Dissolve Detection Based on Image Quality Assessment

    Although many approaches have been proposed for video shot boundary detection, dissolve detection remains an open issue. For a dissolve, we could find that the video frames reveal a “clarity–blur–clarity” visu...

    Weigang Zhang, Chunxi Liu, Qingming Huang, Shuqiang Jiang… in The Era of Interactive Media (2013)

  9. No Access

    Article

    Emerging biotechnological strategies for non-viral antiangiogenic gene therapy

    Angiogenesis has emerged as a promising target of cancer treatment. With the development of biotechnology, major progress has been made in the exploring effective therapies on targeting tumor angiogenesis over...

    Chunxi Liu, Na Zhang in Angiogenesis (2012)

  10. No Access

    Article

    Metal Ions Enhance the Affinities of Flavonoids for Human Serum Albumin in Vitro

    The affinities of apigenin, chrysin, daidzein and quercetin for human serum albumin (HSA) were studied in the presence and absence of Pb2+, Ni2+, Zn2+, Mg2+ and Mn2+. The fluorescence intensities of HSA decrease ...

    Fan Yang, Jie Wang, Chunxi Liu, **aochen Xu, Shunan Shan… in Journal of Solution Chemistry (2012)

  11. No Access

    Article

    Mannan-Modified Solid Lipid Nanoparticles for Targeted Gene Delivery to Alveolar Macrophages

    Cationic solid lipid nanoparticles (SLN) have established themselves during the past decades. They can efficiently bind DNA directly via ionic interaction and mediate gene transfection. One major problem with ...

    Wangyang Yu, Chunxi Liu, Yu Liu, Na Zhang, Wenfang Xu in Pharmaceutical Research (2010)

  12. No Access

    Article

    Enhanced gastrointestinal absorption of N3-O-toluyl-fluorouracil by cationic solid lipid nanoparticles

    This study was aimed to prepare N3-O-toluyl-fluorouracil (TFu) loaded cationic solid lipid nanoparticles (TFu-SLNs) and evaluate the potential of a novel lipid-based drug delivery system to enhance the oral absor...

    Donghua Liu, Chunxi Liu, Weiwei Zou, Na Zhang in Journal of Nanoparticle Research (2010)

  13. Article

    Open Access

    Preparation and Characterization of Cationic PLA-PEG Nanoparticles for Delivery of Plasmid DNA

    The purpose of the present work was to formulate and evaluate cationic poly(lactic acid)-poly(ethylene glycol) (PLA-PEG) nanoparticles as novel non-viral gene delivery nano-device. Cationic PLA-PEG nanoparticl...

    Weiwei Zou, Chunxi Liu, Zhi** Chen, Na Zhang in Nanoscale Research Letters (2009)

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  14. Article

    Open Access

    Knockdown of astrocyte elevated gene-1 inhibits proliferation and enhancing chemo-sensitivity to cisplatin or doxorubicin in neuroblastoma cells

    Astrocyte elevated gene-1 (AEG-1) was originally characterized as a HIV-1-inducible gene in primary human fetal astrocyte. Recent studies highlight a potential role of AEG-1 in promoting tumor progression and met...

    Haiyan Liu, **anrang Song, Chunxi Liu… in Journal of Experimental & Clinical Cancer … (2009)

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