127 Result(s)
within
Chunfang **
Life Sciences
-
Article
Open AccessPRDM14 extinction enables the initiation of trophoblast stem cell formation
Trophoblast stem cells (TSCs) can be chemically converted from embryonic stem cells (ESCs) in vitro. Although several transcription factors (TFs) have been recognized as essential for TSC formation, it remains...
-
Article
Impact of ε-PL treatment on postharvest quality of ‘**xiu’ yellow peach (Prunus persica L.)
To investigate the effectiveness of ε-polylysine (ε-PL) on fruit senescence related to quality and antioxidase activity in ‘**xiu’ yellow peach, and to explore the relationship between cold injury and antioxi...
-
Article
Immunomodulatory Effects of Vitamin D and Zinc on Viral Infection
Several nutrients are crucial in enhancing the immune system and preserving the structural integrity of bodily tissue barriers. Vitamin D (VD) and zinc (Zn) have received considerable interest due to their imm...
-
Article
Open AccessEnhancing cold resistance in Banana (Musa spp.) through EMS-induced mutagenesis, L-Hyp pressure selection: phenotypic alterations, biomass composition, and transcriptomic insights
The cultivation of bananas encounters substantial obstacles, particularly due to the detrimental effects of cold stress on their growth and productivity. A potential remedy that has gained attention is the uti...
-
Article
Glycocholic acid supplementation improved growth performance and alleviated tissue damage in the liver and intestine in Pelteobagrus fulvidraco fed a high-pectin diet
In a study on the anti-nutritional effect of dietary fiber, it was noticed that a high-pectin diet (PEC diet) caused growth retardation, hepatic cholestasis, steatosis, fibrosis, and enteritis accompanied by d...
-
Article
Alpha-lipoic Acid Prevents Bone Loss in Type 2 Diabetes and Postmenopausal Osteoporosis Coexisting Conditions by Modulating the YAP/Glut4 Pathway
This study aims to characterize the bone-protecting effects of Alpha-lipoic acid (ALA), a potent antioxidant, against the detrimental effects of the coexistence of type 2 diabetes mellitus (T2DM) and postmenop...
-
Article
Open AccessTMT quantitative proteomics reveals key proteins relevant to microRNA-1-mediated regulation in osteoarthritis
Osteoarthritis (OA) is the second-commonest arthritis, but pathogenic and regulatory mechanisms underlying OA remain incompletely understood. Here, we aimed to identify the mechanisms associated with microRNA-...
-
Article
Open AccessAdipose transplantation improves olfactory function and neurogenesis via PKCα-involved lipid metabolism in Seipin Knockout mice
Lipodystrophy-associated metabolic disorders caused by Seipin deficiency lead to not only severe lipodystrophy but also neurological disorders. However, the underlying mechanism of Seipin deficiency-induced ne...
-
Article
CCN1 is predominantly elevated in human skin dermis by solar-simulated ultraviolet irradiation and accumulated in dermal extracellular matrix
Skin primarily comprises a collagen-rich extracellular matrix (ECM) that provides structural and functional support to the skin. Aging causes progressive loss and fragmentation of dermal collagen fibrils, lead...
-
Article
Open AccessEstablishing extended pluripotent stem cells from human urine cells
Extended pluripotent stem cells (EPSCs) can contribute to both embryonic and trophectoderm-derived extraembryonic tissues. Therefore, EPSCs have great application significance for both research and industry. H...
-
Article
Open AccessOocyte Arrested at Metaphase II Stage were Derived from Human Pluripotent Stem Cells in vitro
Initiation of meiosis is the most difficult aspect of inducing competent oocytes differentiation from human stem cells in vitro. Human induced pluripotent stem cells (hiPSCs) and embryonic stem cells (hESCs) were...
-
Article
Spatiotemporal evolution of urbanization and its implications to urban planning of the megacity, Shanghai, China
Urbanization has profoundly changed urban landscape patterns and morphologies. Understanding the spatiotemporal evolution of these changes and their driving forces is vital to decision making for urban plannin...
-
Chapter
Role of Biosurfactants in Marine Sediment Remediation of Organic Pollutants
The contamination of marine sediments due to pollutant accumulation is widespread in coastal regions of the world. Of major public concern are pollutants such as polycyclic aromatic hydrocarbons (PAHs), crude ...
-
Chapter
QTL and Candidate Genes for Flax Disease Resistance
Rust, pasmo (PAS), powdery mildew (PM), and Fusarium wilt (FW) are four major diseases of flax, causing yield losses as well as seed and fiber quality reduction. Flax rust resistance is controlled by few major ge...
-
Article
Fungal diversity notes 1512–1610: taxonomic and phylogenetic contributions on genera and species of fungal taxa
This article is the 14th in the Fungal Diversity Notes series, wherein we report 98 taxa distributed in two phyla, seven classes, 26 orders and 50 families which are described and illustrated. Taxa in this stu...
-
Article
Inactivation of Ihh in Sp7-Expressing Cells Inhibits Osteoblast Proliferation, Differentiation, and Bone Formation, Resulting in a Dwarfism Phenotype with Severe Skeletal Dysplasia in Mice
Indian hedgehog (Ihh) is an indispensable paracrine factor for proper tissue patterning, skeletogenesis, and cellular proliferation. Recent genetic studies have revealed critical roles of chondrocyte-derived Ihh ...
-
Article
Downregulation of the paired box gene 3 inhibits the progression of skin cutaneous melanoma by inhibiting c-MET tyrosine kinase
The PAX3 (paired box gene 3) gene is highly expressed in several cancer types. However, its underlying mechanism of action in skin cutaneous melanoma (SKCM) remains unknown.
-
Article
Reduced expression of Collagen 17A1 in naturally aged, photoaged, and UV-irradiated human skin in vivo: Potential links to epidermal aging
Collagen 17A1 (COL17A1) is a transmembrane structural component of the hemidesmosome that mediate adhesion of keratinocytes to the underlying membrane. Recent work in mouse showed that COL17A1 deficiency leads...
-
Article
Transcriptome Profiling of Duodenum Reveals the Importance of Boron Supplementation in Modulating Immune Activities in Rats
As an essential trace element, appropriate boron supplementation can promote immune function of animals. To illustrate the effects of boron in a rat model, RNA-Seq was conducted for the RNA from duodenum after...
-
Article
Microalgae cell disruption and lipid composition and recovery improvements induced by algicidal effects of bacteria
Converting microalgal lipids into biodiesel is considered a promising route in the field of biofuel production. However, the cost of microalgae-based biodiesel is still too high to be economically feasible, es...
