80 Result(s)

Article

Correction: Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits

Jiaojiao Hao, Wenhua Fan, Yizhuo Li… in Journal of Experimental & Clinical Cancer … (2024)

Article

The genome and population genomics of allopolyploid Coffea arabica reveal the diversification history of modern coffee cultivars

Coffea arabica, an allotetraploid hybrid of Coffea eugenioides and Coffea canephora, is the source of approximately 60% of coffee products worldwide, and its cultivated accessions have undergone several populatio...

Jarkko Salojärvi, Aditi Rambani, Zhe Yu, Romain Guyot, Susan Strickler… in Nature Genetics (2024)

Article

Identification of genetic loci jointly influencing COVID-19 and coronary heart diseases

Comorbidities of coronavirus disease 2019 (COVID-19)/coronary heart disease (CHD) pose great threats to disease outcomes, yet little is known about their shared pathology. The study aimed to examine whether co...

Siyue Wang, Hexiang Peng, Feng Chen, Chunfang Liu, Qiwen Zheng… in Human Genomics (2023)

Article

Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling

As a subclass of endogenous stable noncoding RNAs, circular RNAs are beginning to be appreciated for their potential as tumor therapeutics. However, the functions and mechanisms by which circRNAs exert protect...

Deze Zhao, Ye** Dong, Minghao Duan, Dan He… in Journal of Experimental & Clinical Cancer … (2023)

Article

May microbial ecological baseline exist in continental groundwater?

Microbes constitute almost the entire biological community in subsurface groundwater and play an important role in ecological evolution and global biogeochemical cycles. Ecological baseline as a fundamental re...

Sining Zhong, Shungui Zhou, Shufeng Liu, Jiawen Wang, Chenyuan Dang… in Microbiome (2023)

Article

A role for P-selectin and complement in the pathological sequelae of germinal matrix hemorrhage

Germinal matrix hemorrhage is a devastating disease of pre-term infancy commonly resulting in post-hemorrhagic hydrocephalus, periventricular leukomalacia, and subsequent neurocognitive deficits. We demonstrat...

Devin Hatchell, Mohammed Alshareef, Tyler Vasas… in Journal of Neuroinflammation (2023)

Article

Evolution of carbapenem resistance in klebsiella pneumoniae and escherichia coli carrying bla_NDM−1 gene: imipenem exposure results in sustained resistance memory of strains in vitro

Antibiotics exert an outstanding selective pressure on bacteria, forcing their chromosomal gene mutations and drug resistance genes to spread. The objective of this study is to evaluate the expression of the N...

Qiong Zhao, Longhua Sha, Zhaomeng Wu… in Annals of Clinical Microbiology and Antimi… (2023)

Article

Activation of embryonic/germ cell-like axis links poor outcomes of gliomas

It is unclear which core events drive the malignant progression of gliomas. Earlier studies have revealed that the embryonic stem (ES) cell/early PGC state is associated with tumourigenicity. This study was de...

Zhan Ma, Fengyu Zhang, Ji **ong, Haishi Zhang, Hui-Kuan Lin… in Cancer Cell International (2022)

Article

Circadian gene Rev-erbα influenced by sleep conduces to pregnancy by promoting endometrial decidualization via IL-6-PR-C/EBPβ axis

Sleep disturbance can cause adverse pregnancy outcomes by changing circadian gene expression. The potential mechanisms remain unclear. Decidualization is critical for the establishment and maintenance of norma...

Liyuan Cui, Feng Xu, Chunfang Xu, Yan Ding, Songcun Wang… in Journal of Biomedical Science (2022)

Article

Sparse logistic regression revealed the associations between HBV PreS quasispecies and hepatocellular carcinoma

Chronic infection with hepatitis B virus (HBV) has been proved highly associated with the development of hepatocellular carcinoma (HCC).

Jian-an Jia, Shuqin Zhang, **n Bai, Meng Fang, Shipeng Chen… in Virology Journal (2022)

Article

Retraction Note: Bimatoprost-Loaded Silica Shell–Coated Nanoparticles-Laden Soft Contact Lenses to Manage Glaucoma: In Vitro and In Vivo Studies

He **aojie, Jiang Fagang, **g Jun, Wang Chunfang, Li Chengquan… in AAPS PharmSciTech (2022)

Article

Variants in genes related to development of the urinary system are associated with Mayer–Rokitansky–Küster–Hauser syndrome

Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome, also known as Müllerian agenesis, is characterized by uterovaginal aplasia in an otherwise phenotypically normal female with a normal 46,XX karyotype. Previous s...

Chunfang Chu, Lin Li, Shenghui Li, Qi Zhou, ** Zheng, Yu-Di Zhang… in Human Genomics (2022)

Article

Plasma tRNA-derived small RNAs signature as a predictive and prognostic biomarker in lung adenocarcinoma

The prevalence of lung adenocarcinoma (LUAD) has increased, thus novel biomarkers for its early diagnosis is becoming more important than ever. tRNA-derived small RNA (tsRNA) is a new class of non-coding RNA w...

Jun Wang, **anyu Liu, Weifang Cui, Qun **e, Wei Peng… in Cancer Cell International (2022)

Article

Correction to: The tumor suppressor Zinc finger protein 471 suppresses breast cancer growth and metastasis through inhibiting AKT and Wnt/β‑catenin signaling

Chunfang Tao, Juan Luo, Jun Tang, Danfeng Zhou, Shujun Feng… in Clinical Epigenetics (2022)

Article

Two divergent haplotypes from a highly heterozygous lychee genome suggest independent domestication events for early and late-maturing cultivars

Lychee is an exotic tropical fruit with a distinct flavor. The genome of cultivar ‘Feizixiao’ was assembled into 15 pseudochromosomes, totaling ~470 Mb. High heterozygosity (2.27%) resulted in two complete hap...

Guibing Hu, Junting Feng, Xu **ang, Jiabao Wang, Jarkko Salojärvi… in Nature Genetics (2022)