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Article
Clinical and genetic analysis for four Chinese families with Prader–Willi syndrome
Prader–Willi syndrome (PWS) is a complex, genetic, multisystem disorder. Its major clinical features include neonatal hypotonia and failure to thrive, mental retardation, hypogonadism, short hands and feet, hy...
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Article
The interplay of insulin resistance and β-cell dysfunction involves the development of type 2 diabetes in Chinese obeses
Type 2 diabetes mellitus (T2DM) is a heterogeneous disorder characterized by defects in insulin secretion and action and obesity plays an important role in the deterioration of glucose metabolism. In the prese...
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Article
Elevated serum levels of interleukin-18 are associated with insulin resistance in women with polycystic ovary syndrome
Overproduction of proinflammatory factors is associated with obesity and diabetes. Interleukin (IL)-18 as a member of IL-1 cytokine family is increased in obese, in diabetic, and even in polycystic ovary syndr...