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    Article

    Clinical and genetic analysis for four Chinese families with Prader–Willi syndrome

    Prader–Willi syndrome (PWS) is a complex, genetic, multisystem disorder. Its major clinical features include neonatal hypotonia and failure to thrive, mental retardation, hypogonadism, short hands and feet, hy...

    Yu-wen Zhang, Hui-ying Jia, Jie Hong, Yan Ge, Hui-jie Zhang, Chun-fang Shen in Endocrine (2009)

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    The interplay of insulin resistance and β-cell dysfunction involves the development of type 2 diabetes in Chinese obeses

    Type 2 diabetes mellitus (T2DM) is a heterogeneous disorder characterized by defects in insulin secretion and action and obesity plays an important role in the deterioration of glucose metabolism. In the prese...

    Jie Hong, Wei-Qiong Gu, Yi-Fei Zhang, Yi-Sheng Yang, Chun-Fang Shen, Min Xu in Endocrine (2007)

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    Elevated serum levels of interleukin-18 are associated with insulin resistance in women with polycystic ovary syndrome

    Overproduction of proinflammatory factors is associated with obesity and diabetes. Interleukin (IL)-18 as a member of IL-1 cytokine family is increased in obese, in diabetic, and even in polycystic ovary syndr...

    Yi-fei Zhang, Yi-sheng Yang, Jie Hong, Wei-qiong Gu, Chun-fang Shen, Min Xu in Endocrine (2006)