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  1. Article

    Open Access

    Astrocyte-derived SerpinA3N promotes neuroinflammation and epileptic seizures by activating the NF-κB signaling pathway in mice with temporal lobe epilepsy

    Impaired activation and regulation of the extinction of inflammatory cells and molecules in injured neuronal tissues are key factors in the development of epilepsy. SerpinA3N is mainly associated with the acut...

    Chong Liu, Xue-Min Zhao, Qiao Wang, Ting-Ting Du in Journal of Neuroinflammation (2023)

  2. Article

    Open Access

    Subthalamic nucleus-deep brain stimulation improves autonomic dysfunctions in Parkinson’s disease

    To study the effects of subthalamic nucleus-deep brain stimulation (STN-DBS) on autonomic dysfunctions in Parkinson’s disease (PD) patients.

    Feng Zhang, Feng Wang, Cong-Hui Li, Ji-Wei Wang, Chun-Lei Han in BMC Neurology (2022)

  3. Article

    Open Access

    The risk of shoulder pain after laparoscopic surgery for infertility is higher in thin patients

    Postlaparoscopic shoulder pain (PLSP) is a common clinical problem that needs to be addressed by medical professionals who are currently perform laparoscopic surgeries. The purpose of this study was to determi...

    **n You Li, Ming Tian, Ai Zhi Li, Chun Lei Han, Ke Zhong Li in Scientific Reports (2021)

  4. Article

    Open Access

    Long non-coding RNA H19 contributes to apoptosis of hippocampal neurons by inhibiting let-7b in a rat model of temporal lobe epilepsy

    Temporal lobe epilepsy (TLE) is one of the most common types of intractable epilepsy, characterized by hippocampal neuron damage and hippocampal sclerosis. Long noncoding RNAs (lncRNAs) have been increasingly ...

    Chun-Lei Han, Ming Ge, Yun-Peng Liu, Xue-Min Zhao, Kai-Liang Wang in Cell Death & Disease (2018)

  5. Article

    Open Access

    LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy

    Astrocyte and microglia activation are well-known features of temporal lobe epilepsy that may contribute to epileptogenesis. However, the mechanisms underlying glia activation are not well understood. Long non...

    Chun-Lei Han, Ming Ge, Yun-Peng Liu, Xue-Min Zhao in Journal of Neuroinflammation (2018)

  6. Article

    Open Access

    Parkinsonism-hyperpyrexia syndrome after withdrawal of antiparkinsonian drugs and deep brain stimulation surgery

    Parkinsonism-hyperpyrexia syndrome (PHS) is a rare but potentially fatal condition in patients with Parkinson’s disease. Deep brain stimulation (DBS) is a widely used and efficacious treatment for advanced Par...

    Chun-Lei Han, Yan Ge, Da-Wei Meng, Jian-Guo Zhang in Chinese Neurosurgical Journal (2017)