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  1. No Access

    Article

    Leveraging federated learning for boosting data privacy and performance in IVF embryo selection

    To study the effectiveness of federated learning in in vitro fertilization on embryo evaluation tasks.

    Chun-I Lee, Chii-Ruey Tzeng, Monty Li in Journal of Assisted Reproduction and Genet… (2024)

  2. Article

    Open Access

    Associations between the artificial intelligence scoring system and live birth outcomes in preimplantation genetic testing for aneuploidy cycles

    Several studies have demonstrated that iDAScore is more accurate in predicting pregnancy outcomes in cycles without preimplantation genetic testing for aneuploidy (PGT-A) compared to KIDScore and the Gardner c...

    Chun-I Lee, Chun-Chia Huang, Tsung-Hsien Lee in Reproductive Biology and Endocrinology (2024)

  3. Article

    Open Access

    Innovative technology for evaluation of sperm DNA double-strand breaks diagnoses male factor infertility and prevents reproductive failures

    Neutral comet assay has been available for two decades to evaluate sperm double-strand breaks (DSBs). However, its clinical usability is limited due to its complex and time-consuming procedure, as well as the ...

    Tse-En Wang, Chun-I. Lee, Chun-Chia Huang, Hui-Mei Tsao in Scientific Reports (2023)

  4. Article

    Open Access

    Increased incidence of live births in implanted day 5 versus day 6 blastocysts following single embryo transfers with PGT-A

    Elective single-embryo transfers of euploid or low-level mosaic blastocysts were analyzed in this retrospective study to determine the correlations of live birth (LB) probability with embryonic developmental f...

    Chien-Hong Chen, Chun-I Lee, Chun-Chia Huang, Hsiu-Hui Chen in Scientific Reports (2023)

  5. No Access

    Article

    Live motile sperm sorting device for enhanced sperm-fertilization competency: comparative analysis with density-gradient centrifugation and microfluidic sperm sorting

    A live motile sperm sorting device (LensHooke® CA0) developed to prevent the deleterious effects of centrifugation was evaluated comparatively with conventional density-gradient centrifugation (DGC) and microflui...

    Cheng-Teng Hsu, Chun-I. Lee, Fong-Sian Lin in Journal of Assisted Reproduction and Genet… (2023)

  6. Article

    Open Access

    Biphasic oxygen tension promotes the formation of transferable blastocysts in patients without euploid embryos in previous monophasic oxygen cycles

    This study evaluated whether the concentration of biphasic O2 (5–2%) promotes the formation of qualified blastocysts (QBs) and euploid blastocysts and the probability of cycles with transferable blastocysts. The ...

    Hsiu-Hui Chen, Chun-I Lee, Chun-Chia Huang, En-Hui Cheng in Scientific Reports (2023)

  7. Article

    Open Access

    Estimating the causal effect of embryo transfer day on clinical in vitro fertilization outcomes using propensity score matching

    For women undergoing in vitro fertilization (IVF), the clinical benefit of embryo transfer at the blastocyst stage (Day 5) versus cleavage stage (Day 3) remains controversial. The purpose of this study is to c...

    Han-Chih Hsieh, Chun-I Lee, En-Yu Lai, Jia-Ying Su in BMC Pregnancy and Childbirth (2021)

  8. No Access

    Article

    End-to-end deep learning for recognition of ploidy status using time-lapse videos

    Our retrospective study is to investigate an end-to-end deep learning model in identifying ploidy status through raw time-lapse video.

    Chun-I Lee, Yan-Ru Su, Chien-Hong Chen in Journal of Assisted Reproduction and Genet… (2021)

  9. No Access

    Article

    Healthy live births from transfer of low-mosaicism embryos after preimplantation genetic testing for aneuploidy

    This study evaluated the potential viability of embryos with low mosaicism level (< 50%) by comparing the clinical outcomes of single mosaic versus euploid blastocyst transfer. In addition, the live birth outc...

    Chun-I Lee, En-Hui Cheng, Maw-Sheng Lee in Journal of Assisted Reproduction and Genet… (2020)

  10. No Access

    Article

    Visualization of Facial Expression Deformation Applied to the Mechanism Improvement of Face Robot

    The static and dynamic realistic effects of the appearance are essential but challenging targets in the development of human face robots. Human facial anatomy is the primary theoretical foundation for designin...

    Li-Chieh Cheng, Chyi-Yeu Lin, Chun-Chia Huang in International Journal of Social Robotics (2013)

  11. No Access

    Article

    Nitric oxide modulates mitochondrial activity and apoptosis through protein S-nitrosylation for preimplantation embryo development

    Previous studies reported that patients with endometriosis had excess nitric oxide (NO) in the reproductive tract and poor embryo development in IVF cycles. This study aims to elucidate the effects of NO on ea...

    Tsung-Hsien Lee, Maw-Sheng Lee in Journal of Assisted Reproduction and Genet… (2013)

  12. No Access

    Article

    Association of creatin kinase B and peroxiredoxin 2 expression with age and embryo quality in cumulus cells

    The purpose of this study was to identify age-related oocyte or embryo markers suitable for non-invasive analysis, as women over 38 years of age experience diminished pregnancy and ovulation rates.

    Maw-Sheng Lee, Chung-Hsien Liu in Journal of Assisted Reproduction and Genet… (2010)

  13. Article

    Open Access

    Impact of female age and male infertility on ovarian reserve markers to predict outcome of assisted reproduction technology cycles

    This study was designed to assess the capability of ovarian reserve markers, including baseline FSH levels, baseline anti-Müllerian hormone (AMH) levels, and antral follicle count (AFC), as predictors of live ...

    Tsung-Hsien Lee, Chung-Hsien Liu, Chun-Chia Huang in Reproductive Biology and Endocrinology (2009)

  14. No Access

    Article

    Orientation relations between carbon nanotubes grown by chemical vapour deposition and residual iron-containing catalysts

    Orientation relationships between the growth direction of carbon nanotubes and encapsulated residual iron-containing particles have been determined using transmission electron microscopy. The nanotubes that ar...

    Che-Yi Wen, Chun-Chia Huang, Huy-Zu Cheng, Hong-Yang Lu in Journal of Materials Science (2008)

  15. No Access

    Article

    The association between polypronucleate zygote formation with certain motion characteristics of sperm and IVF outcome

    To determine the efficiency of sperm motion characteristics as predictors for normal (2PN) and polypronulceate (PPN) zygotes in IVF.

    Tsung-Hsien Lee, Chung-Hsien Liu in Journal of Assisted Reproduction and Genet… (2008)

  16. No Access

    Article

    DNA Fragmentation, Mitochondrial Dysfunction and Chromosomal Aneuploidy in the Spermatozoa of Oligoasthenoteratozoospermic Males

    Purpose : This study determined the incidence of sperm nuclear DNA fragmentation, mitochondrial dysfunction, and chromosomal aneuploidy. The results were correlated with the semen analysis parameters and fertili...

    Chung-Hsien Liu, Hui-Mei Tsao in Journal of Assisted Reproduction and Genet… (2004)