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  1. Article

    Open Access

    OsMAPK6 phosphorylation and CLG1 ubiquitylation of GW6a non-additively enhance rice grain size through stabilization of the substrate

    The chromatin modifier GRAIN WEIGHT 6a (GW6a) enhances rice grain size and yield. However, little is known about its gene network determining grain size. Here, we report that MITOGEN-ACTIVED PROTEIN KINASE 6 (...

    Chen Bai, Gao-Jie Wang, **ao-Hui Feng, Qiong Gao, Wei-Qing Wang in Nature Communications (2024)

  2. Article

    Open Access

    A new model using deep learning to predict recurrence after surgical resection of lung adenocarcinoma

    This study aimed to develop a deep learning (DL) model for predicting the recurrence risk of lung adenocarcinoma (LUAD) based on its histopathological features. Clinicopathological data and whole slide images ...

    Pil-Jong Kim, Hee Sang Hwang, Gyuheon Choi, Hyun-Jung Sung in Scientific Reports (2024)

  3. Article

    Open Access

    NME3 is a gatekeeper for DRP1-dependent mitophagy in hypoxia

    NME3 is a member of the nucleoside diphosphate kinase (NDPK) family localized on the mitochondrial outer membrane (MOM). Here, we report a role of NME3 in hypoxia-induced mitophagy dependent on its active site...

    Chih-Wei Chen, Chi Su, Chang-Yu Huang, Xuan-Rong Huang in Nature Communications (2024)

  4. Article

    Open Access

    County-scale dataset indicating the effects of disasters on crops in Taiwan from 2003 to 2022

    A lack of crop disaster datasets has limited the exploration of the influence of small-scale disasters on crops. Because disasters are often defined on the basis of human impact, disaster databases may underes...

    Yuan-Chih Su, Yuan Shen, Chun-Yi Wu, Bo-Jein Kuo in Scientific Data (2024)

  5. Article

    Open Access

    Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice

    Cancer cachexia is a systemic metabolic syndrome characterized by involuntary weight loss, and muscle and adipose tissue wasting. Mechanisms underlying cachexia remain poorly understood. Leukemia inhibitory fa...

    Xue Yang, Jianming Wang, Chun-Yuan Chang, Fan Zhou, Juan Liu in Nature Communications (2024)

  6. Article

    Open Access

    Author Correction: Continuous aerosol monitoring and comparison of aerosol exposure based on smoke dispersion distance and concentrations during oxygenation therapy

    Chih‑Chieh Wu, Wei‑Lun Chen, Cheng‑Wei Tseng, Yung‑Cheng Su in Scientific Reports (2023)

  7. Article

    Open Access

    Using machine learning algorithm to analyse the hypothyroidism complications caused by radiotherapy in patients with head and neck cancer

    Machine learning algorithms were used to analyze the odds and predictors of complications of thyroid damage after radiation therapy in patients with head and neck cancer. This study used decision tree (DT), ra...

    Tsair-Fwu Lee, Shen-Hao Lee, Chin-Dar Tseng, Chih-Hsueh Lin in Scientific Reports (2023)

  8. Article

    Open Access

    Continuous aerosol monitoring and comparison of aerosol exposure based on smoke dispersion distance and concentrations during oxygenation therapy

    This study evaluated the aerosol exposure risks while using common noninvasive oxygenation devices. A simulated mannequin was designed to breathe at a minute ventilation of 20 L/min and used the following oxyg...

    Chih-Chieh Wu, Wei-Lun Chen, Cheng-Wei Tseng, Yung-Cheng Su in Scientific Reports (2023)

  9. Article

    Open Access

    Structural insights into functional properties of the oxidized form of cytochrome c oxidase

    Cytochrome c oxidase (CcO) is an essential enzyme in mitochondrial and bacterial respiration. It catalyzes the four-electron reduction of molecular oxygen to water and harnesses the chemical energy to translocate...

    Izumi Ishigami, Raymond G. Sierra, Zhen Su, Ariana Peck, Cong Wang in Nature Communications (2023)

  10. Article

    Open Access

    Lrig1-expression confers suppressive function to CD4+ cells and is essential for averting autoimmunity via the Smad2/3/Foxp3 axis

    Regulatory T cells (Treg) are CD4+ T cells with immune-suppressive function, which is defined by Foxp3 expression. However, the molecular determinants defining the suppressive population of T cells have yet to be...

    Jae-Seung Moon, Chun-Chang Ho, Jong-Hyun Park, Kyungsoo Park in Nature Communications (2023)

  11. Article

    Open Access

    Ce-mediated molecular tailoring on gigantic polyoxometalate {Mo132} into half-closed {Ce11Mo96} for high proton conduction

    Precise synthesis of polyoxometalates (POMs) is important for the fundamental understanding of the relationship between the structure and function of each building motif. However, it is a great challenge to re...

    Xue-**n Li, Cai-Hong Li, Ming-Jun Hou, Bo Zhu, Wei-Chao Chen in Nature Communications (2023)

  12. Article

    Open Access

    A comparative analysis of aerosol exposure and prevention strategies in bystander, pre-hospital, and inpatient cardiopulmonary resuscitation using simulation manikins

    To evaluate aerosol exposure risk and prevention strategies during bystander, pre-hospital, and inpatient cardiopulmonary resuscitation (CPR). This study compared hands-only CPR, CPR with a surgical or N95 mas...

    Tzu-Yao Hung, Chung-Shiung Wen, Sheng-Han Yu, Yi-Chang Chen in Scientific Reports (2023)

  13. Article

    Open Access

    Interval timing relative to response inhibition in the differential reinforcement of low-rate responding in normally develo** young adults

    With recent proposal suggesting the multifaceted nature of impulsivity, researchers have been intrigued by the question of whether the impulsive behaviour measured in the traditionally psychological paradigms ...

    Tsung-Han Yang, Ruey-Ming Liao, Chung-I. Su, Chun-Yi Chien in Scientific Reports (2023)

  14. Article

    Open Access

    Morel–Lavallee lesions and number of surgeries for associated injuries predict surgical site infection risk following pelvic ring injury osteosynthesis

    We examined the incidence and causative factors of surgical site infection (SSI) following osteosynthesis for pelvic ring injury by reviewing the data of 97 consecutive patients with pelvic ring injuries treat...

    Chih-Yang Lai, Po-Ju Lai, I-Chuan Tseng, Chun-Yi Su, Yung-Heng Hsu in Scientific Reports (2023)

  15. Article

    Open Access

    Author Correction: Rhythm control without catheter ablation may have benefits beyond stroke prevention in rivaroxaban-treated non-permanent atrial fibrillation

    Wei-Ru Chiou, Po-Lin Lin, Chun-Che Huang, Jen-Yu Chuang in Scientific Reports (2023)

  16. Article

    Open Access

    Incidence trends and spatial distributions of lung adenocarcinoma and squamous cell carcinoma in Taiwan

    Lung cancer is the second most common cancer in Taiwan. After Taiwan implemented the Tobacco Hazards Prevention Act in 1997, smoking rates declined. However, the incidence rates of lung cancer for both sexes a...

    Hsin-I Liu, Chun-Ju Chiang, Shih-Yung Su, **g-Rong Jhuang in Scientific Reports (2023)

  17. Article

    Open Access

    Abdominal pain is a main manifestation of delayed bleeding after splenic injury in patients receiving non-operative management

    Delayed bleeding is a major issue in patients with high-grade splenic injuries who receive non-operative management (NOM). While only few studies addressed the clinical manifestations of delayed bleeding in th...

    Yu-Cheng Su, Chia-Yu Ou, Tsung-Han Yang, Kuo-Shu Hung, Chun-Hsien Wu in Scientific Reports (2022)

  18. Article

    Open Access

    Photoredox C–H functionalization leads the site-selective phenylalanine bioconjugation

    Site-selectively chemical bioconjugation of peptides and proteins can improve the therapeutic exploration of modified protein drugs. Only 3.8% natural abundance of phenylalanine in protein and nearly 90% of pr...

    Yue Weng, Chun-Jen Su, Haoyang Jiang, Chien-Wei Chiang in Scientific Reports (2022)

  19. Article

    Open Access

    Environment is associated with chytrid infection and skin microbiome richness on an amphibian rich island (Taiwan)

    Growing evidence suggests that the origins of the panzootic amphibian pathogens Batrachochytrium dendrobatidis (Bd) and Batrachochytrium salamandrivorans (Bsal) are in Asia. In Taiwan, an island hotspot of high a...

    Dirk S. Schmeller, Tina Cheng, Jennifer Shelton, Chun-Fu Lin in Scientific Reports (2022)

  20. Article

    Open Access

    The association of pericardial fat and peri-aortic fat with severity of nonalcoholic fatty liver disease

    Visceral adipose tissue (VAT) is associated with central obesity, insulin resistance and metabolic syndrome. However, the association of body-site specific adiposity and non-alcoholic fatty liver disease (NAFL...

    Chun-Wei Lee, Chun-Ho Yun, Wen-Hung Huang, Ta-Chuan Hung in Scientific Reports (2022)

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