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Article
Open AccessDIPS (Dystonia Image-based Programming of Stimulation: a prospective, randomized, double-blind crossover trial)
Deep brain stimulation of the internal globus pallidus is an effective treatment for dystonia. However, there is a large variability in clinical outcome with up to 25% non-responders even in highly selected pr...
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Article
Open AccessMechanical properties of CAD/CAM-fabricated in comparison to conventionally fabricated functional regulator 3 appliances
Manufacturing of Fränkel's functional regulator 3 (FR3) is complicated and requires extensive knowledge from the dental technician. To determine whether FR3s produced by CAD/CAM techniques (CAD-FR3) meet simil...
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Article
Open AccessEvaluation of magnetic resonance imaging artifacts caused by fixed orthodontic CAD/CAM retainers—an in vitro study
Magnetic resonance imaging (MRI) image quality can be severely impaired by artifacts caused by fixed orthodontic retainers. In clinical practice, there is a trend towards using computer-aided design/computer-a...
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Article
Open AccessExpression of apoptosis repressor with caspase recruitment domain (ARC) in familial adenomatous polyposis (FAP) adenomas and its correlation with DNA mismatch repair proteins, p53, Bcl-2, COX-2 and beta-catenin
Colorectal familial adenomatous polyposis (FAP) adenomas exhibit a uniform pathogenetic basis caused by a germline mutation in the adenomatous polyposis gene (APC), but the molecular changes leading to their deve...
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Chapter and Conference Paper
The Production Cultural Biorhythm as a New LEAN Learning Process
Bottlenecks limit value streams, extend lead times and thus cause high costs. ADaM24 provides a new approach to bottleneck problems by offering Advanced Data Management over 24 h for individual and organizatio...
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Chapter and Conference Paper
Practical Estimation of the Impact of a Reduction of the Number of Kanban Cards on the Delivery Performance
Kanban systems are the best-known variant of pull systems and a cornerstone of lean manufacturing. Kanban systems help to maintain a good material availability in relation to the inventory. One of the main adj...
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Chapter and Conference Paper
A Framework and Qualitative Comparison on Different Approaches to Improve the Lean Skillset
Lean Manufacturing is considered to be one of the major frameworks in improving manufacturing performance. Yet, a majority of lean improvement projects fail to generate a benefit for the organization. The prob...
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Chapter and Conference Paper
An Enhanced Data-Driven Algorithm for Shifting Bottleneck Detection
Bottleneck detection is vital for improving production capacity or reducing production time. Many different methods exist, although only a few of them can detect shifting bottlenecks. The active period method ...
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Chapter and Conference Paper
A Simulation-Based Performance Comparison Between Flow Shops and Job Shops
It is well known in manufacturing that a flow shop usually outperforms a job shop for comparable products. This paper aims to understand the impact of routing variability on WIP inventory, lead time, and deliv...
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Chapter
Advances in Production Management Systems: Issues, Trends, and Vision Towards 2030
Since its inception in 1978, the IFIP Working Group (WG) 5.7 on Advances in Production Management Systems (APMS) has played an active role in the fields of production and production management. The Working Gro...
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Chapter and Conference Paper
Proposal of a Beer Distribution Game Considering Waste Management and the Bullwhip Effect
The beer distribution game is a role-playing board game that also helps people learn about the importance of supply chain management. However, the game does not include the major difficulties in managing food...
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Chapter and Conference Paper
The Power of Six: Relation Between Time and Money in Manufacturing for Segments of the Value Stream
A major influence on the cost of a product is the time it takes to make this product. Traditional cost accounting can grasp part of this relation, but misses many critical aspects of having a faster time to th...
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Article
CaboACC: Cabozantinib beim fortgeschrittenen Nebennierenkarzinom nach Versagen der Standardtherapie
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Chapter and Conference Paper
Practical Boundary Case Approach for Kanban Calculation on the Shop Floor Subject to Variation
Determining the number of kanban in a pull production is essential for a good system performance. While this is simple in a static case, it becomes much more challenging if the system is subject to variations,...
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Chapter and Conference Paper
Options for Maintaining Weak FIFO in Parallel Queues
Maintaining a FIFO sequence is a common aspect of manufacturing, especially in lean manufacturing. This can easily be realized by having FIFO lanes, where items are added at one end and removed at the other en...
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Chapter and Conference Paper
A Small Dice Game for the Kingman Formula
There are three main factors influencing the waiting time of a single-arrival single-process system: the utilization, the fluctuation of the arrival, and the fluctuation of the process time. The influence of t...
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Chapter and Conference Paper
Effect of Prioritization on the Waiting Time
In industry, it is common to prioritize some orders over others. This is done to reduce the lead time and waiting time of these prioritized orders, hence the customer will get the order earlier than otherwise....
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Chapter and Conference Paper
Relationship Between Variants and Inventory Under Consideration of the Replenishment Time
It is common wisdom that the finished goods inventory increases with the number of variants stored in that inventory. However, to the best of our knowledge, this has never been verified. This paper presents re...
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Chapter and Conference Paper
Bottleneck Prediction Using the Active Period Method in Combination with Buffer Inventories
Knowing the bottleneck is one of the keys to improving a production system. The active period method is one approach to detect shifting bottlenecks that most other bottleneck detection methods have problems wi...
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Chapter and Conference Paper
Supermarkets vs. FIFO Lanes: A Comparison of Work-in-Process Inventories and Delivery Performance
Pull production is a key element for a lean manufacturing system. In pull production, buffer inventories between two processes can be implemented either through a FIFO lane as part of a kanban loop, or through...
