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  1. Article

    Open Access

    Fructooligosaccharides benefits on glucose homeostasis upon high-fat diet feeding require type 2 conventional dendritic cells

    Diet composition impacts metabolic health and is now recognized to shape the immune system, especially in the intestinal tract. Nutritional imbalance and increased caloric intake are induced by high-fat diet (...

    Adélaïde Gélineau, Geneviève Marcelin, Melissa Ouhachi in Nature Communications (2024)

  2. Article

    Open Access

    Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide

    The host-microbiota co-metabolite trimethylamine N-oxide (TMAO) is linked to increased cardiovascular risk but how its circulating levels are regulated remains unclear. We applied “explainable” machine learning, ...

    Petros Andrikopoulos, Judith Aron-Wisnewsky, Rima Chakaroun in Nature Communications (2023)

  3. Article

    Open Access

    Author Correction: Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

    A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20412-9.

    Antonio Molinaro, Pierre Bel Lassen, Marcus Henricsson, Hao Wu in Nature Communications (2020)

  4. Article

    Open Access

    Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

    Microbiota-host-diet interactions contribute to the development of metabolic diseases. Imidazole propionate is a novel microbially produced metabolite from histidine, which impairs glucose metabolism. Here, we...

    Antonio Molinaro, Pierre Bel Lassen, Marcus Henricsson, Hao Wu in Nature Communications (2020)

  5. No Access

    Article

    Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

    Microbiome community ty** analyses have recently identified the Bacteroides2 (Bact2) enterotype, an intestinal microbiota configuration that is associated with systemic inflammation and has a high prevalence in...

    Sara Vieira-Silva, Gwen Falony, Eugeni Belda, Trine Nielsen in Nature (2020)

  6. Article

    Open Access

    Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue

    Adipose tissue contains a variety of immune cells, which vary in abundance and phenotype with obesity. The contribution of immune cell-derived factors to inflammatory, fibrotic and metabolic alterations in adi...

    Charles Caër, Christine Rouault, Tiphaine Le Roy, Christine Poitou in Scientific Reports (2017)