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  1. Article

    Open Access

    Evaluation and Application of a PET Tracer in Preclinical and Phase 1 Studies to Determine the Brain Biodistribution of Minzasolmin (UCB0599)

    Minzasolmin (UCB0599) is an orally administered, small molecule inhibitor of ASYN misfolding in development as a potential disease-modifying therapy for Parkinson’s disease. Here we describe the preclinical de...

    Joël Mercier, Massimo Bani, Anny-Odile Colson in Molecular Imaging and Biology (2024)

  2. Article

    Open Access

    Clinical Bridging Studies and Modeling Approach for Implementation of a Patient Centric Sampling Technique in Padsevonil Clinical Development

    Volumetric absorptive microsampling (VAMS) techniques have gained popularity these last years as innovative tool for collection of blood pharmacokinetic (PK) samples in clinical trials as they offer many advan...

    Hester Kramer, Ceyhun Bicer, Christian Otoul, Chiara Rospo in The AAPS Journal (2023)