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  1. Article

    Open Access

    Optical coherence tomography angiography suggests different retinal pathologies in multiple sclerosis and Sjögren’s syndrome

    While retinal vessel changes are evident in the eyes of patients with relapsing–remitting multiple sclerosis (RRMS), changes in the vasculature of possible MS mimics such as primary Sjögren’s syndrome (pSS) re...

    Elisabeth Wolf, Rebecca Wicklein, Lilian Aly, Christoph Schmaderer in Journal of Neurology (2024)

  2. Article

    Open Access

    Exacerbation of central serous chorioretinopathy during trauma-confronting psychotherapy– a case report

    Psychotherapy for post-traumatic stress disorder, in particular trauma-confronting psychotherapy, can be associated with increased stress. However, research on the somatic impact and psychosomatic interactions...

    Eva Schäflein, Christian Mardin, Eva Morawa, Sophia Rudolf, Yesim Erim in BMC Psychiatry (2024)

  3. Article

    Open Access

    Glaucoma detection using non-perfused areas in OCTA

    Multiple ophthalmic diseases lead to decreased capillary perfusion that can be visualized using optical coherence tomography angiography images. To quantify the decrease in perfusion, past studies have often u...

    Julia Schottenhamml, Tobias Würfl, Stefan Ploner, Lennart Husvogt in Scientific Reports (2024)

  4. Article

    Open Access

    Investigation of OCTA Biomarkers in Fabry Disease: A Long Term Follow-Up of Macular Vessel Area Density and Foveal Avascular Zone Metrics

    Retinal microvasculature is known to be altered in patients with Fabry disease (FD). We aimed to investigate the long-term changes in macular microvasculature and explore a reliable retinal biomarker for treat...

    Katerina Hufendiek, Migle Lindziute, Jessica Kaufeld in Ophthalmology and Therapy (2023)

  5. Article

    Open Access

    Toxic retrobulbar neuritis due to recurrent nonsteroidal antiinflammatory drug-exacerbated respiratory disease-based chronic sinusitis in the left sphenoid sinus: a case report

    Abrupt visual impairment constitutes a medical urgency, necessitating an interdisciplinary diagnostic and therapeutic approach owing to the broad spectrum of potential etiologies, thereby engaging numerous med...

    Mirco Schapher, Jacob Bruegel, Fabian Guener in Journal of Medical Case Reports (2023)

  6. No Access

    Chapter and Conference Paper

    A Keypoint Detection and Description Network Based on the Vessel Structure for Multi-modal Retinal Image Registration

    Ophthalmological imaging utilizes different imaging systems, such as color fundus, infrared, fluorescein angiography, optical coherence tomography (OCT) or OCT angiography. Multiple images with different modal...

    Aline Sindel, Bettina Hohberger in Bildverarbeitung für die Medizin 2022 (2022)

  7. Article

    Open Access

    Maternal SARS-CoV-2 infection during pregnancy: possible impact on the infant

    The risk and potential consequences of mother-to-child transmission of severe acute respiratory syndrome-coronavirus type 2 (SARS-CoV-2) during pregnancy are still a matter of debate. We studied the impact of ...

    Patrick Morhart, Christian Mardin, Manfred Rauh in European Journal of Pediatrics (2022)

  8. No Access

    Article

    Relative Mikro- und Makropapillen – eine Herausforderung in der Glaukomdiagnostik mit der optischen Kohärenztomographie?

    Die optische Kohärenztomographie ermöglicht eine hochauflösende Darstellung und Vermessung der Glaukom relevanten Strukturen des Auges am hinteren Pol. Minimale Randsaumweite, retinale Nervenfaserschicht- und ...

    Christian Mardin in Der Ophthalmologe (2021)

  9. No Access

    Article

    Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

    Chiea Chuen Khor, Tin Aung, Francesca Pasutto, Janey Wiggs and colleagues report a global genome-wide association study of exfoliation syndrome and a fine-map** analysis of a previously identified disease-as...

    Tin Aung, Mineo Ozaki, Mei Chin Lee, Ursula Schlötzer-Schrehardt in Nature Genetics (2017)

  10. Article

    Correction: Corrigendum: A common variant map** to CACNA1A is associated with susceptibility to exfoliation syndrome

    Nat. Genet. 47, 387–392 (2015); published online 23 February 2015; corrected online 9 March 2015; corrected after print 27 April 2015 In the version of this article initially published, the name of author Afsa...

    Tin Aung, Mineo Ozaki, Takanori Mizoguchi, R Rand Allingham, Zheng Li in Nature Genetics (2015)

  11. No Access

    Article

    A common variant map** to CACNA1A is associated with susceptibility to exfoliation syndrome

    Tin Aung, Chiea-Chuen Khor and colleagues report the results of a genome-wide association study of exfoliation syndrome. They replicate a known association at LOXL1 and identify a previously unreported associatio...

    Tin Aung, Mineo Ozaki, Takanori Mizoguchi, R Rand Allingham, Zheng Li in Nature Genetics (2015)

  12. No Access

    Article

    Successful remission induction with a combination therapy of rituximab, cyclophosphamide, and steroids in a patient with refractory optic neuritis in Wegener’s granulomatosis

    A 56-year old patient with a history of limited Wegener's granulomatosis presented with signs and symptoms of optic neuritis. Radiologic signs of orbital inflammation were absent. Testing of visual acuity and ...

    Cord Huchzermeyer, Christian Mardin, Leonard Holbach in Clinical Rheumatology (2013)

  13. No Access

    Article

    Quadrant pattern ERG with SLO stimulation in normals and glaucoma patients

    • Background: The pattern ERG (PERG) is one of the promising methods for investigation of glaucoma and may detect it at an early stage. The purpose of this study was to test the usefulness of the scanning lase...

    Folkert Horn, Christian Mardin in Graefe's Archive for Clinical and Experime… (1996)