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    Chapter

    Telomeres and Cellular Aging

    Human somatic cells undergo only a limited number of divisions in vitro before they withdraw from the cell division cycle and enter a permanent state of proliferation arrest. This arrest is accompanied by a varie...

    Christian D. Toouli, Roger R. Reddel in Aging of Cells in and Outside the Body (2003)

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    Article

    Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit

    We directly compared two methods of immortalizing human mammary epithelial cells (HMECs). Cells were transfected with an expression plasmid either for hTERT, the catalytic subunit of telomerase, or for the sim...

    Christian D Toouli, Lily I Huschtscha, Axel A Neumann, Jane R Noble… in Oncogene (2002)