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Open AccessLate spontaneous posterior capsule rupture with single-piece hydrophobic acrylic intraocular lens dislocation
In this study, we described and discussed the late onset spontaneous posterior capsule rupture with intraocular lens (IOL) dislocation years after uncomplicated cataract surgery and implantation of hydrophobic...
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Article
Open AccessMoxifloxacin releasing intraocular implant based on a cross-linked hyaluronic acid membrane
Intraocular antibiotic delivery is an important technique to prevent bacterial infection after ophthalmic surgery, such as cataract surgery. Conventional drug delivery methods, such as antibiotic eye drops, ha...
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Article
Open AccessNitric oxide attenuated transforming growth factor-β induced myofibroblast differentiation of human keratocytes
Nitric oxide (NO) has the potential to modulate myofibroblast differentiation. In this study, we investigated the effect of exogenous NO on the myofibroblast differentiation of human keratocytes using sodium n...
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Open AccessEvaluation of moxifloxacin-induced cytotoxicity on human corneal endothelial cells
Moxifloxacin hydrochloride (MXF) is widely used for the prevention of bacterial endophthalmitis after intraocular surgeries. However, the safety issue of intracameral injection of MXF for human corneal endothe...
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Open AccessDevelopment of a novel hyaluronic acid membrane for the treatment of ocular surface diseases
Ocular surface diseases (OSD) can cause serious visual deterioration and discomfort. Commercial artificial tear solution containing hyaluronic acid (HA) show excellent biocompatibility and unique viscoelastic ...
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Article
Open AccessIgG4-related disease presenting as recurrent scleritis combined with optic neuropathy
We report a case of atypical presentation of IgG4-related disease (IgG4-RD) with recurrent scleritis and optic nerve involvement.
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Article
Open AccessA case of severe flare reaction observed in HLA B27 associated acute anterior uveitis
Anterior chamber flare reaction refers to the light reflection from the protein in aqueous humor. We report a case of very severe flare reaction observed in human leukocyte antigen (HLA)- B27 associated acute ...
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Article
Open AccessComparison of cytotoxicities and anti-allergic effects of topical ocular dual-action anti-allergic agents
To investigate the cytotoxicities of the topical ocular dual-action anti-allergic agents (alcaftadine 0.25%, bepotastine besilate 1.5%, and olopatadine HCL 0.1%) on human corneal epithelial cells (HCECs) and t...
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Open AccessToxic anterior segment syndrome-an updated review
Toxic anterior segment syndrome (TASS) can be a rare complication of anterior segment surgery. Here we reviewed the most recent advances in the understanding of TASS.
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Open AccessThe Antibiofilm efficacy of nitric oxide on soft contact lenses
To investigate the antibiofilm efficacy of nitric oxide (NO) on soft contact lenses.
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Article
Open AccessSafety of Nonporous Silica Nanoparticles in Human Corneal Endothelial Cells
Nonporous silica nanoparticles (SiNPs) are promising drug carrier platforms for intraocular drug delivery. In this study, we investigated the safety of three different sizes of SiNPs (50, 100, and 150 nm) in a...
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Article
Open AccessLow recurrence rate of anchored conjunctival rotation flap technique in pterygium surgery
To report the recurrence rate for an anchored conjunctival rotation flap technique in primary pterygium surgery.
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Open AccessAn Evaluation of the in vivo Safety of Nonporous Silica Nanoparticles: Ocular Topical Administration versus Oral Administration
Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of...
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Open AccessEffect of Nitric Oxide on Human Corneal Epithelial Cell Viability and Corneal Wound Healing
Although the wound healing effects of nitric oxide (NO) are known, the mechanism by which NO modulates corneal wound healing remains unclear. In this study, we investigated the effect of exogenous NO donor (NaNO2
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Article
Open AccessReversible opacification of hydrophobic acrylic intraocular lens- two cases report
The opacification of the intraocular lens (IOL) can cause significant visual deterioration. It is known that opacity of hydrophobic acrylic IOLs is rare. We report 2 cases of reversible optic opacification of ...
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Article
Open AccessThe Effect of Silica Nanoparticles on Human Corneal Epithelial Cells
Ocular drug delivery is an interesting field in current research. Silica nanoparticles (SiNPs) are promising drug carriers for ophthalmic drug delivery. However, little is known about the toxicity of SiNPs on ...
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Article
Open AccessThe effect of Vaccinium uliginosum extract on tablet computer-induced asthenopia: randomized placebo-controlled study
To investigate the alleviation effect of Vaccinium uliginosum extract (DA9301) on tablet computer-induced asthenopia.
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Article
Subclinical primary retinal pathology in neuromyelitis optica spectrum disorder
Foveal thickness may be a more sensitive indicator of primary retinal pathology than retinal nerve fiber layer thickness since the fovea contains no or sparse retinal nerve fiber layer, which coalesces into ax...