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Article
ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the olfactory bulb (OB) ...
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Article
Benefits of Hepatitis C Viral Eradication: A Real-World Nationwide Cohort Study in Taiwan
Chronic hepatitis C (CHC) increases the risk of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). This nationwide cohort study assessed the effectiveness of viral eradication of CHC.
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Article
Improved energy storage performances in (1−x)Bi0.5Na0.5TiO3–xSr0.7Bi0.2(Zn1/3Nb2/3)O3 relaxor ferroelectrics
Lead-free dielectric ceramic capacitors (DCCs) characterized by wide operating temperatures and high recoverable energy storage density (Wrec) obtained under low electric fields (LEFs) have garnered significant a...
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Article
Triggering triplet excitons of carbon nanodots through nanospace domain confinement for multicolor phosphorescence in aqueous solution
Easy non-radiative decay property of long-lived triplet excitons in aqueous solution obstructs their applications in aquatic surroundings. Recently reported phosphorescence phenomena in aqueous solution have e...
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Article
A systematic review and meta-analysis of the role of perineal hydrodissection in perioperative, oncologic, and functional outcomes for patients undergoing robot-assisted radical prostatectomy
This study aims to compare the perioperative, oncological, and functional outcomes of perineal hydrodissection (HD) with standard treatment (ST) in patients undergoing robot-assisted radical prostatectomy. We ...
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Article
Experimental quantum computational chemistry with optimized unitary coupled cluster ansatz
Quantum computational chemistry has emerged as a potential application of quantum computing. Hybrid quantum-classical computing methods, such as variational quantum eigensolvers, have been designed as promisin...
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Article
Comparative analysis of perioperative outcomes in obese patients undergoing robot-assisted radical prostatectomy (RARP) versus open radical prostatectomy (ORP): a systematic review and meta-analysis
The purpose of this study was to conduct a comparative analysis of the perioperative outcomes associated with robot-assisted laparoscopic prostatectomy (RARP) versus open radical prostatectomy (ORP) in the obe...
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Article
Open AccessHigh-throughput screening unveils nitazoxanide as a potent PRRSV inhibitor by targeting NMRAL1
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) poses a major threat to the global swine industry, yet effective prevention and control measures remain elusive. This study unveils Nitazoxanide (NTZ...
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Article
Rational design multi-color-emissive chemiluminescent carbon nanodots in a single solvothermal reaction
Recently, the chemiluminescence (CL) induced by carbon nanodots (CDs) has intrigued researchers’ extensive interests in various applications due to its special light emission principle. However, the difficulty...
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Article
Open AccessReal-World Efficacy and Safety of Universal 8-Week Glecaprevir/Pibrentasvir for Treatment-Naïve Patients from a Nationwide HCV Registry in Taiwan
Eight-week glecaprevir/pibrentasvir (GLE/PIB) is indicated for treatment-naïve (TN) patients with chronic hepatitis C (CHC), with or without compensated cirrhosis. Given that the Taiwanese government is commit...
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Article
Painlevé analysis, auto-Bäcklund transformations, bilinear form and analytic solutions on some nonzero backgrounds for a \((2{+}1)\) -dimensional generalized nonlinear evolution system in fluid mechanics and plasma physics
Fluid mechanics concerns the mechanisms of liquids, gases and plasmas and the forces on them. We aim to investigate a \((2+1)\) ...
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Article
Open AccessComparison of children and adults in deep brain stimulation for Tourette Syndrome: a large-scale multicenter study of 102 cases with long-term follow-up
Deep brain stimulation (DBS) is a promising therapy for refractory Gilles de la Tourette syndrome (GTS). However, its long-term efficacy, safety, and recommended surgical age remain controversial, requiring ev...
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Article
Lightweight insulating oil-well cement filled with hollow glass microspheres and numerical simulation of its unsteady heat transfer process
During offshore natural gas extraction, the formation of hydrates in the wellbore poses a crucial issue that affects flow safety. There is a need to find a reliable solution to establish a wellbore with excell...
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Article
Open AccessIdentification of the mutual gliding locus as a factor for gut colonization in non-native bee hosts using the ARTP mutagenesis
The gut microbiota and their hosts profoundly affect each other’s physiology and evolution. Identifying host-selected traits is crucial to understanding the processes that govern the evolving interactions betw...
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Article
Open AccessWhite matter alterations and their associations with biomarkers and behavior in subjective cognitive decline individuals: a fixel-based analysis
Subjective cognitive decline (SCD) is an early stage of dementia linked to Alzheimer's disease pathology. White matter changes were found in SCD using diffusion tensor imaging, but there are known limitations ...
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Article
Open AccessEV71 5’UTR interacts with 3D protein affecting replication through the AKT-mTOR pathway
EV71 is one of the important pathogens of Hand-foot-and-mouth disease (HFMD), which causes serious neurological symptoms. Several studies have speculated that there will be interaction between 5′UTR and 3D pro...
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Article
Open AccessSubtype prediction of intrahepatic cholangiocarcinoma using dynamic contrast-enhanced ultrasound
The study aimed to investigate the predictive value of dynamic contrast-enhanced ultrasound (DCE-US) in differentiating small-duct (SD) and large-duct (LD) types of intrahepatic cholangiocarcinoma (ICC).
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Article
Theoretical study of superradiant masing with solid-state spins at room temperature
Steady-state superradiance and superradiant lasing attract significant attentions in the field of optical lattice clocks, but have not been achieved yet due to the technical challenges and atom loss problem. I...
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Article
Open AccessCross-site validation of lung cancer diagnosis by electronic nose with deep learning: a multicenter prospective study
Although electronic nose (eNose) has been intensively investigated for diagnosing lung cancer, cross-site validation remains a major obstacle to be overcome and no studies have yet been performed.
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Article
Biomechanical evaluation of various rigid internal fixation modalities for condylar-base-associated multiple mandibular fractures: A finite element analysis
Condylar-base-associated multiple mandibular fractures are more prevalent than single ones. Direct trauma to mandibular symphysis, body or angle are prone to induce indirect condylar fracture. However, little ...
