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  1. Article

    Open Access

    Estimation of footprints of the canine stifle ligaments using deformable shape templates of bones

    Knowledge regarding the ligament footprints in the canine stifle is essential for biomechanical modeling of the joint and patient-specific surgical planning for anatomical ligament reconstruction. The present ...

    Yu-Ying Lin, Cheng-Chung Lin, Ching-Ho Wu in Scientific Reports (2024)

  2. Article

    Open Access

    Ex vivo biomechanical evaluation of extracapsular stabilization with quasi-isometric points in canine cranial cruciate ligament-deficient stifles

    Cranial cruciate ligament (CCL) disease is one of the most common causes of lameness in dogs. The extracapsular stabilization (ECS) utilizing bone anchors and monofilament nylon leader was an alternative treat...

    Wei-Ru Hsu, Cheng-Chung Lin, Cheng-Yuan Sun, Ching-Ho Wu in BMC Veterinary Research (2023)

  3. Article

    Open Access

    Topical applications of allogeneic adipose-derived mesenchymal stem cells ameliorate the canine keratoconjunctivitis sicca

    Canine keratoconjunctivitis sicca (KCS) is predominantly an immune-mediated disease. Current therapy of canine KCS is mainly by immunosuppressant, but the effectiveness was limited in some patients. In the pas...

    Li-Ning Wei, Ching-Ho Wu, Chung-Tien Lin, I-Hsuan Liu in BMC Veterinary Research (2022)

  4. Article

    A real-time camera-based adaptive breathing monitoring system

    Breathing is one of the vital signs used to assess the physical health of a subject. Non-contact-based measurements of both breathing rate and changes in breathing rate help monitor health condition of subject...

    Yu-Ching Lee, Abdan Syakura in Medical & Biological Engineering & Computi… (2021)

  5. Article

    Open Access

    Hypochlorite-induced porcine model of peritoneal fibrosis through the activation of IL1β-CX3CL1-TGFβ1 signal axis

    Patients with kidney failure rely on life-saving peritoneal dialysis to facilitate waste exchange and maintain homeostasis of physical conditions. However, peritoneal dialysis often results in peritoneal fibro...

    Yu-Ting Hsu, Ching-Ho Wu, Chun-Yuan Chao, Yu-Syuan Wei in Scientific Reports (2020)

  6. Article

    Open Access

    Expression of HIF-1α and VEGF in feline mammary gland carcinomas: association with pathological characteristics and clinical outcomes

    The microenvironment within solid malignant tumors, including feline mammary gland carcinomas (FMGCs), is commonly hypoxic, possibly due to the lack of functional blood vessels in rapidly proliferating neoplas...

    Bo Chen, Susanne Je-Han Lin, Wen-Ta Li, Hui-Wen Chang in BMC Veterinary Research (2020)

  7. Article

    Open Access

    Evaluation of a multibody kinematics optimization method for three-dimensional canine pelvic limb gait analysis

    Skin marker-based three-dimensional kinematic gait analysis were commonly used to assess the functional performance and movement biomechanics of the pelvic limb in dogs. Unfortunately, soft tissue artefact wou...

    Cheng-Chung Lin, Ching-Ho Wu, Po-Yen Chou, Shi-Nuan Wang in BMC Veterinary Research (2020)

  8. Article

    Open Access

    Evaluation of antiviral activity of Bacillus licheniformis-fermented products against porcine epidemic diarrhea virus

    Bacillus licheniformis (B. licheniformis) is commonly used as probiotic and its secondary metabolites are attractive anti-microbial candidate. In the present study, we aimed to evaluate the antiviral activity of ...

    Ju-Yi Peng, Yi-Bing Horng, Ching-Ho Wu, Chia-Yu Chang, Yen-Chen Chang in AMB Express (2019)

  9. Article

    Open Access

    Role of nuclear factor-kappa B in feline injection site sarcoma

    Chronic inflammation has been implicated in sarcomagenesis. Among various factors, activation of nuclear factor-kappa B (NF-κB) signaling pathway has been documented being able to target genes associated with ...

    Cheng-Shun Hsueh, Ching-Ho Wu, Cheng-Hsin Shih in BMC Veterinary Research (2019)

  10. Article

    Open Access

    Quantification of three-dimensional soft tissue artifacts in the canine hindlimb during passive stifle motion

    Three-dimensional joint kinematics during canine locomotion are commonly measured using skin marker-based stereophotogrammetry technologies. However, marker-related errors caused by the displacement of the ski...

    Cheng-Chung Lin, Chia-Lin Chang, Ming Lu, Tung-Wu Lu in BMC Veterinary Research (2018)

  11. Article

    Open Access

    Evaluation of ranges of motion of a new constrained acetabular prosthesis for canine total hip replacement

    Total hip replacement (THR) is considered to be the most effective treatment option for advanced osteoarthritis of the hip in large breed dogs. However, a proportion of post-THR patients suffer prosthesis disl...

    Ching-Ho Wu, Cheng-Chung Lin, Tung-Wu Lu, Sheng-Mao Hou in BioMedical Engineering OnLine (2013)