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  1. Article

    Open Access

    Lobohedleolide suppresses hepatitis C virus replication via JNK/c-Jun-C/EBP-mediated down-regulation of cyclooxygenase-2 expression

    Hepatitis C virus (HCV) chronically infects 2–3% people of the global population, which leads to liver cirrhosis and hepatocellular carcinoma. Drug resistance remains a serious problem that limits the effectiv...

    Chun-Kuang Lin, Chin-Kai Tseng, Chih-Chuang Liaw, Chiung-Yao Huang… in Scientific Reports (2018)

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  2. Article

    Open Access

    Cyclooxygenase‐2 facilitates dengue virus replication and serves as a potential target for develo** antiviral agents

    Cyclooxygenase-2 (COX-2) is one of the important mediators of inflammation in response to viral infection, and it contributes to viral replication, for example, cytomegalovirus or hepatitis C virus replication...

    Chun-Kuang Lin, Chin-Kai Tseng, Yu-Hsuan Wu, Chih-Chuang Liaw… in Scientific Reports (2017)

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  3. Article

    Open Access

    Vitroprocines, new antibiotics against Acinetobacter baumannii, discovered from marine Vibrio sp. QWI-06 using mass-spectrometry-based metabolomics approach

    A robust and convenient research strategy integrating state-of-the-art analytical techniques is needed to efficiently discover novel compounds from marine microbial resources. In this study, we identified a se...

    Chih-Chuang Liaw, Pei-Chin Chen, Chao-Jen Shih, Sung-Pin Tseng… in Scientific Reports (2015)

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