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Article
Open AccessTargeting and internalizing PEGylated nanodrugs to enhance the therapeutic efficacy of hematologic malignancies by anti-PEG bispecific antibody (mPEG × CD20)
PEGylated nanoparticles (PEG-NPs) are not effective for hematologic malignancies as they lack the enhanced permeability and retention effect (EPR effect). Tumor-targeted PEG-NPs can systemically track lymphoma...
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Chapter and Conference Paper
Neuroscience, Neuroaesthetics, Semiotics and Effective Communication of COVID-19 Warning Information
The need to indicate the significant adverse effects of COVID-19 and the behaviour desired from the population to address this offer an excellent context to consider the varied approaches to providing such inf...
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Article
Open AccessDouble attack strategy for leukemia using a pre-targeting bispecific antibody (CD20 Ab-mPEG scFv) and actively attracting PEGylated liposomal doxorubicin to enhance anti-tumor activity
Tumor-targeted nanoparticles hold great promise as new tools for therapy of liquid cancers. Furthermore, the therapeutic efficacy of nanoparticles can be improved by enhancing the cancer cellular internalization.
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Article
Open AccessUtilization of silicon nanowire field-effect transistors for the detection of a cardiac biomarker, cardiac troponin I and their applications involving animal models
This study develops an ultrasensitive electrical device, the silicon nanowire-field effect transistor (SiNW-FET) for detection of cardiac troponin I (cTnI) in obesity induced myocardial injury. The biosensor d...
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Article
Open AccessHumanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer
Develo** a universal strategy to improve the specificity and sensitivity of PEGylated nanoaparticles (PEG-NPs) for assisting in the diagnosis of tumors is important in multimodality imaging. Here, we develop...
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Article
High-level Sp1 is Associated with Proliferation, Invasion, and Poor Prognosis in Astrocytoma
Astrocytoma is the most common and the most lethal primary brain tumor in adults. Grade IV glioblastoma is usually refractory to currently available surgical, chemotherapeutic, and radiotherapeutic treatments....
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Article
Open AccessMutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis
Prostate cancer (PCA), one of the most common malignant tumors in men, is the second leading cause of cancer deaths in males worldwide. We report here that PCA models harboring conditional LSL/KrasG12D or BRAFF-V...
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Article
Open AccessComparison of efficacy and safety of preoperative Chemoradiotherapy in locally advanced upper and middle/lower rectal cancer
We aimed to explore the efficacy and safety profile of preoperative neoadjuvant chemoradiation (NACRT) in locally advanced rectal cancer (LARC) in upper rectum versus middle/lower rectum.
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Article
Open AccessAbnormal white matter integrity in rapists as indicated by diffusion tensor imaging
Recent research has documented structural brain abnormalities in various criminal offenders. However, there have been few brain imaging studies of sex offenders, and none on white matter integrity. The curren...
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Article
Added value of diffusion-weighted imaging to MR cholangiopancreatography for the diagnosis of bile duct dilatations
To investigate the added value of diffusion-weighted imaging (DWI) when used with conventional T2-weighted magnetic resonance (MR) imaging (T2WI) and MR cholangiopancreatography (MRCP) for diagnosing bile duct...
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Article
Lowering radiation dose during dedicated colorectal cancer MDCT: comparison of low tube voltage and sinogram-affirmed iterative reconstruction at 80 kVp versus blended dual-energy images in a population of patients with low body mass index
To assess the diagnostic accuracy, cancer staging, image quality, and radiation dose of 80-kVp computed tomography (CT) images for patients with colorectal cancers (CRCs) using sinogram-affirmed iterative reco...
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Article
Altered brain activation during response inhibition and error processing in subjects with Internet gaming disorder: a functional magnetic imaging study
The aim of the present study was to evaluate the impulsivity and brain correlates of response inhibition and error processing among subjects with Internet gaming disorder (IGD). We evaluated the response inhib...
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Article
Posterior parietal cortex and visuospatial control in near and far space
Neuropsychological studies of patients with visuospatial neglect have shown differences in perceptual deficits for information in near space (i.e. near to the body) and information in far space. It has been su...
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Article
Targeted Herceptin–dextran iron oxide nanoparticles for noninvasive imaging of HER2/neu receptors using MRI
A novel magnetic resonance imaging (MRI) contrast agent containing Herceptin is reported. The surfaces of superparamagnetic iron oxide nanoparticles were modified with dextran and conjugated with Herceptin (He...
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Article
Differentiation of gastric ulcers with MDCT
It is important to differentiate malignant from benign gastric ulcers (GUs) because the early detection of malignancy offers the best prognosis and is essential for planning optimal therapy. However, the diffe...
