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Open AccessApplication of response surface methodology and quantitative NMR for the optimum extraction, characterization, and quantitation of Antrodia cinnamomea triterpenoids
Antrodia cinnamomea (AC) is a treasured Asian medicinal mushroom, which has attracted attention due to recent research on its effectiveness in targeting a variety of serious ailments such as cancer and liver dise...
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Open AccessArecae pericarpium extract induces porcine lower-esophageal-sphincter contraction via muscarinic receptors
Gastroesophageal reflux disease (GERD) is associated with lower esophageal sphincter (LES) incompetence. In some patients, GERD is refractory to acid reduction therapy which is the main treatment for GERD. So ...
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Bioactive polyketides from the pathogenic fungus of Epicoccum sorghinum
We discovered and identified a series of characteristic substances, including one new polyketide, epicorepoxydon B, of the important pathogenic fungus, Epicoccum sorghinum, of sorghum. The fungal extract and some...
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Natural products development under epigenetic modulation in fungi
Natural products derived from microorganisms play a key role in the discovery and development of drug candidates. Several drugs have originated from secondary metabolites or their derivatives from microorganis...
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Laparoscopic vesico-ureteral reimplantation with Lich–Gregoir approach in children: medium term results of 159 renal units in 117 children
Vesico-ureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. Surgery is an important part of its management. Laparoscopic ureteric reimplantation using...
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Erectile Dysfunction
Erectile dysfunction (ED) is defined as the consistent inability to achieve or maintain an erection. This may affect around 50% of men between the ages of 40 and 70, while persistent ED affects about 5% of men...