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Article
Open AccessPatient preference on once-daily oral versus injectable androgen deprivation therapy for Asian patients with advanced prostate cancer
The study aimed at investigating prostate cancer patients’ choice of androgen deprivation treatment (ADT) and possible factors that would affect their preferences of ADT.
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Article
Open AccessCardiovascular disease risk assessment and multidisciplinary care in prostate cancer treatment with ADT: recommendations from the APMA PCCV expert network
Androgen deprivation therapy (ADT) is the mainstay approach for prostate cancer (PCa) management. However, the most commonly used ADT modality, gonadotropin-releasing hormone (GnRH) agonists, has been associat...
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Article
Open AccessOne-year clinical outcomes of MR-guided stereotactic body radiation therapy with rectal spacer for patients with localized prostate cancer
This prospective study aimed to investigate adaptive magnetic resonance (MR)-guided stereotactic body radiation therapy (MRgSBRT) with rectal spacer for localized prostate cancer (PC) and report 1-year clinica...
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Article
Industrial sources of per- and polyfluoroalkyl substances (PFAS) to a sewershed in Ontario, Canada
Per- and polyfluoroalkyl substances (PFAS) are ubiquitous in the environment despite global regulatory action to restrict their use in industrial processes and products. The objective of this reconnaissance sa...
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Article
Open AccessA multi-center international study to evaluate the safety, functional and oncological outcomes of irreversible electroporation for the ablation of prostate cancer
Irreversible electroporation (IRE) is a novel technique to treat localized prostate cancer with the aim of achieving oncological control while reducing related side effects. We present the outcomes of localize...
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Article
Open AccessMajor adverse cardiovascular events of enzalutamide versus abiraterone in prostate cancer: a retrospective cohort study
While the cardiovascular risks of androgen receptor pathway inhibitors have been studied, they were seldom compared directly. This study compares the risks of major adverse cardiovascular events (MACE) between...
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Article
Transperineal Targeted Microwave Ablation (TMA) of localized prostate cancer guided by MRI-Ultrasound fusion and organ-based tracking: a pilot study
To investigate the efficacy of transperineal targeted microwave ablation (TMA) in treating localized prostate cancer (PCa).
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Article
Oncological results and cancer control definition in focal therapy for Prostate Cancer: a systematic review
Focal therapy (FT) is a promising alternative to whole-gland treatments for Localized Prostate Cancer. Ten different FT modalities have been described in literature. However, FT is not yet recommended by the I...
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Article
Functional outcomes and safety of focal therapy for prostate cancer: a systematic review on results and patient-reported outcome measures (PROMs)
Focal therapy (FT) is a promising alternative with curative intent for Low- to Intermediate-risk localized Prostate Cancer (PCa), claiming better functional outcomes and safety profile than standard whole-glan...
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Article
Global burden and temporal trends of lower urinary tract symptoms: a systematic review and meta-analysis
Lower urinary tract symptoms (LUTS) are common complaint in urology practice and affecting the quality of life for patients. This article aims to perform a systematic review and meta-analysis on the global pre...
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Article
Open AccessTemporal trends in cardiovascular burden among patients with prostate cancer receiving androgen deprivation therapy: a population-based cohort study
Although androgen deprivation therapy (ADT) is associated with cardiovascular risks, the extent and temporal trends of cardiovascular burden amongst patients with prostate cancer receiving ADT are unclear.
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Article
A prospective evaluation of the effect of finasteride on prostate health index (phi)
5-alpha reductase inhibitor (5ARI) reduces prostate-specific antigen (PSA) by half but its effect on prostate health index (phi) is unknown. This study aims to investigate this effect and to enable accurate inter...
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Article
Open AccessImpact of previous malignancy at diagnosis on oncological outcomes of upper tract urothelial carcinoma
The evidence of prognostic factors and individualized surveillance strategies for upper tract urothelial carcinoma are still weak.
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Article
Mate-pair genome sequencing reveals structural variants for idiopathic male infertility
Currently, routine genetic investigation for male infertility includes karyoty** analysis and PCR for Y chromosomal microdeletions to provide prognostic information such as sperm retrieval success rate. Howe...
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Article
Enhancement of prostate cancer diagnosis by machine learning techniques: an algorithm development and validation study
To investigate the value of machine learning(ML) in enhancing prostate cancer(PCa) diagnosis.
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Article
Initial Prostate Health Index (phi) and phi density predicts future risk of clinically significant prostate cancer in men with initial negative prostate biopsy: a 6-year follow-up study
Men with elevated prostate-specific antigen (PSA) and initial negative prostate biopsy may have risk of prostate cancer (PCa) in the future. The role of Prostate Health Index (phi) in determining future PCa risk ...
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Article
Radical nephroureterectomy for UTUC conferred survival benefits irrespective of age and comorbidities
We investigated the effects of age, American Society of Anesthesiologists Physical Status Classification (ASA) grading and Charlson Comorbidity Index (CCI) on the survival outcomes of upper tract urothelial ca...
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Article
One step closer between dietary pattern and cancer prevention
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Article
Technique, outcome and changes in prostate dimensions in patients with urinary retention managed by aquablation
This study aimed to investigate the functional and urodynamic outcome of Aquablation in patients with acute urinary retention (AUR) on catheters.
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Article
Open AccessEndothelial nitric oxide synthase (eNOS)-NO signaling axis functions to promote the growth of prostate cancer stem-like cells
Accumulating evidence supports that prostate cancer stem-like cells (PCSCs) play significant roles in therapy resistance and metastasis of prostate cancer. Many studies also show that nitric oxide (NO) synthes...
