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Article
The role of comorbidity indices and histochemical markers in surgically resected and non-resected primary central nervous system lymphoma
The role of surgical resection in primary central nervous system lymphoma (PCNSL) was not recognized until recently. However, prognostic factors for surgically treated PCNSL remain unclear. In the present stud...
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Article
Stem Cell Therapy in Spinal Cord Injury-Induced Neurogenic Lower Urinary Tract Dysfunction
Spinal cord injury (SCI) is a devastating condition that enormously affects an individual’s health and quality of life. Neurogenic lower urinary tract dysfunction (NLUTD) is one of the most important sequelae ...
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Article
Brain tissue oxygen tension monitoring for traumatic brain injury: limitations and alternatives
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Article
Open AccessSciatic nerve stimulation alleviates acute neuropathic pain via modulation of neuroinflammation and descending pain inhibition in a rodent model
Neuropathic pain (NP) is characterized by abnormal activation of pain conducting pathways and manifests as mechanical allodynia and thermal hypersensitivity. Peripheral nerve stimulation is used for treatment ...
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Article
Open AccessThe rs1256328 (ALPL) and rs12654812 (RGS14) Polymorphisms are Associated with Susceptibility to Calcium Nephrolithiasis in a Taiwanese population
Nephrolithiasis is a common disease affecting almost all populations, with an increasing prevalence over the past decades. Previous studies revealed several functional polymorphisms associated with the pathoge...
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Article
Open AccessPromyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons
Promyelocytic leukemia zinc finger (Plzf), a transcriptional regulator involved in a lot of important biological processes during development, has been implied to maintain neural stem cells and inhibit their d...
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Article
Open AccessZnf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
The brain predominantly expressed RING finger protein, Znf179, is known to be important for embryonic neuronal differentiation during brain development. Downregulation of Znf179 has been observed in motor neur...
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Article
Open AccessAuthor Correction: Znf179 induces differentiation and growth arrest of human primary glioblastoma multiforme in a p53-dependent cell cycle pathway
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Article
Open AccessZnf179 induces differentiation and growth arrest of human primary glioblastoma multiforme in a p53-dependent cell cycle pathway
Malignant glioblastoma multiforme (GBM) is an aggressive brain tumor with strong local invasive growth and a poor prognosis. One probable way to manipulate GBM cells toward a less invasive status is to reprogr...
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Article
Open AccessTherapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS
In the central nervous system regions of the sporadic and familial FTLD and ALS patients, TDP-43 has been identified as the major component of UBIs inclusions which is abnormally hyperphosphorylated, ubiquitin...
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Article
Open AccessSoluble epoxide hydrolase inhibitor enhances synaptic neurotransmission and plasticity in mouse prefrontal cortex
The soluble epoxide hydrolase (sEH) is an important enzyme chiefly involved in the metabolism of fatty acid signaling molecules termed epoxyeicosatrienoic acids (EETs). sEH inhibition (sEHI) has proven to be p...
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Article
Open AccessAnalysis of the interaction between Zinc finger protein 179 (Znf179) and promyelocytic leukemia zinc finger (Plzf)
Zinc finger protein 179 (Znf179), also known as ring finger protein 112 (Rnf112), is a member of the RING finger protein family and plays an important role in neuronal differentiation. To investigate novel mec...
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Article
The Decline of “Chinese Identity” in Taiwan?! — An Analysis of Survey Data from 1992 to 2012
This paper attempts to provide a concrete response and analysis to the decline of Chinese identity in Taiwan. Our focus is on the problem of “Chinese identity” and how this identity is gradually fading, as is ...
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Article
Evaluation of friction in ultrasonic vibration-assisted press forging using double cup extrusion tests
Ultrasonic energy is applied to a die in an ultrasonic vibration-assisted metal forming process, and the die is used to deform the workpiece. The friction between die and workpiece decreases when ultrasonic vi...
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Article
Finite element analysis on neck-spinning process of tube at elevated temperature
Tube spinning process is a metal forming process used in the manufacture of axisymmetric products and has been widely used in various applications. Finite element analysis has been successfully applied to the ...
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Article
Choledochal Cysts: Differences Between Pediatric and Adult Patients
Choledochal cysts in children and adults are believed to be different, but direct comparison between them is lacking in the literature. This study was aimed to identify the clinicopathological differences betw...
