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Article
Genetic structural differences between responders and non-responders to interferon therapy for chronic hepatitis-B patients
Interferon-α therapy has become a main stay of treatment for hepatitis-B patients. The sustained remission rates are around 30%, and the factors determining response are poorly defined. Our study aimed to sear...
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Article
Discovery of genetic difference between asthmatic children with high IgE level and normal IgE level by whole genome linkage disequilibrium map** using 763 autosomal STR markers
The genome-wide linkage disequilibrium screen for loci associated with genetic difference between allergic and nonallergic asthma was conducted with 763 autosomal STR markers and included 190 asthmatic childre...
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Article
Association study using combination analysis of SNP and STRP markers: CD14 promoter polymorphism and IgE level in Taiwanese asthma children
Chromosome 5, especially the 5q31-33 region, may contain one or more loci to control total serum IgE as well as asthma and bronchial hyperresponsiveness. To investigate the regions related with IgE level in ch...
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Article
Heterozygosities and allelic frequencies of 811 dinucleotide-repeat marker loci in the Taiwanese population
To evaluate basic informativeness of commercially available microsatellite markers in theTaiwanese population, 190 unrelated Taiwanese children were genotyped using ABI PRISM Linkage Map** Set-HD5. The avera...
