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  1. No Access

    Article

    Optimization of Strategy for Modified mRNA Inducing Cardiac-Specific Expression in Mice

    Lipid nanoparticle (LNP)-coated-modified RNA(modRNA) has been developed for enhancing the stability of modRNA, but it tends to accumulate in liver. The current study aimed to optimize strategy for increasing c...

    Chenxing Huang, Jianguo Jia, Kejia **… in Journal of Cardiovascular Translational Re… (2023)

  2. Article

    Open Access

    Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload

    Progressive cardiac fibrosis accelerates the development of heart failure. Here, we aimed to explore serum Wnt5a and Wnt11 levels in hypertension patients, the roles of Wnt5a and Wnt11 in cardiac fibrosis and ...

    Yan Zou, Le Pan, Yi Shen, **ang Wang, Chenxing Huang, Hao Wang… in Cell Death & Disease (2021)

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