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Article
Open AccessA cuproptosis-related gene expression signature predicting clinical prognosis and immune responses in intrahepatic cholangiocarcinoma detected by single-cell RNA sequence analysis
Cholangiocarcinoma represents a malignant neoplasm originating from the hepatobiliary tree, with a subset of tumors develo** inside the liver. Intrahepatic cholangiocarcinomas (ICC) commonly exhibit an asymp...
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Chapter and Conference Paper
Domain Incremental Learning for EEG-Based Seizure Prediction
When building seizure prediction systems, the typical research scenario is patient-specific. In this scenario, the model is limited to performing well for individual patients and cannot acquire knowledge trans...
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Article
Open AccessPLAGL1 is associated with prognosis and cell proliferation in pancreatic adenocarcinoma
Emerging evidence has shown the crucial roles of pleomorphic adenoma gene (PLAG) family genes in multiple cancers. However, their functions and mechanisms in pancreatic adenocarcinoma (PAAD) remain poorly underst...
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Article
Open AccessSYT8 promotes pancreatic cancer progression via the TNNI2/ERRα/SIRT1 signaling pathway
Pancreatic cancer is a highly lethal malignancy due to failures of early detection and high metastasis in patients. While certain genetic mutations in tumors are associated with severity, the molecular mechani...
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Article
Sunitinib is effective and tolerable in Chinese patients with advanced pancreatic neuroendocrine tumors: a multicenter retrospective study in China
To determine the efficacy and safety of sunitinib in Chinese patients with unresectable or metastatic pancreatic neuroendocrine tumors (pNETs) and the clinical significance of steady-state sunitinib serum con...
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Article
Loss of polarity protein AF6 promotes pancreatic cancer metastasis by inducing Snail expression
Pancreatic cancer (PC) is a particularly lethal form of cancer with high potential for metastasis to distant organs. Disruption of cell polarity is a hallmark of advanced epithelial tumours. Here we show that ...
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Article
Open AccessRetraction Note: Growth inhibition and apoptosis induced by 6-fluoro-3-formylchromone in hepatocellular carcinoma
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Article
Downregulation of CPE regulates cell proliferation and chemosensitivity in pancreatic cancer
Pancreatic cancer (PC) is one of the most common cancers worldwide and a leading cause of cancer-related death. Discovering novel targets is a key for its therapy. Carboxypeptidase E (CPE), a subtype of the pr...
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Article
miR-208-Induced Epithelial to Mesenchymal Transition of Pancreatic Cancer Cells Promotes Cell Metastasis and Invasion
The aim of this study was to investigate the role of miR-208 in the invasion and metastasis of pancreatic cancer cells and the underlying molecular mechanism. miR-208 mimic, miR-208 inhibitor and NC were trans...
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Article
Open AccessRETRACTED ARTICLE: Growth inhibition and apoptosis induced by 6-fluoro-3-formylchromone in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most lethal and prevalent cancers in human population. The 6-fluoro-3-formylchromone (FCC) has been shown to have anti-tumor activity against various tumor cells. H...
