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  1. Article

    Open Access

    A novel N6-Deoxyadenine methyltransferase METL-9 modulates C. elegans immunity via dichotomous mechanisms

    N6-Methyldeoxyadenine (6mA) has been rediscovered as a DNA modification with potential biological function in metazoans. However, the physiological function and regulatory mechanisms regarding the establishment,....

    Chengchuan Ma, Tingling Xue, Qi Peng, Jie Zhang, Jialiang Guan… in Cell Research (2023)

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    Article

    N6-methyldeoxyadenine is a transgenerational epigenetic signal for mitochondrial stress adaptation

    N6-methyldeoxyadenine (6mA), a major type of DNA methylation in bacteria, represents a part of restriction-modification systems to discriminate host genome from invader DNA1. With the recent advent of more sensit...

    Chengchuan Ma, Rong Niu, Tianxiao Huang, Li-Wa Shao, Yong Peng… in Nature Cell Biology (2019)