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Article
Open AccessApplication of deep learning to predict the low serum albumin in new hemodialysis patients
Serum albumin level is a crucial nutritional indicator for patients on dialysis. Approximately one-third of patients on hemodialysis (HD) have protein malnutrition. Therefore, the serum albumin level of patien...
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Article
Open AccessAssociation of proportion of the HDL-cholesterol subclasses HDL-2b and HDL-3 and macrovascular events among patients undergoing hemodialysis
Altered high-density lipoprotein cholesterol (HDL-C) subclass distribution in hemodialysis (HD) patients is well documented. Aim of this study is to investigate the relationship between HDL-C subclass distribu...
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Article
Open AccessTime-varying serum albumin levels and all-cause mortality in prevalent peritoneal dialysis patients: a 5-year observational study
In this study, we investigated the association of time-varying serum albumin levels with mortality over a 5-year period in one cohort of patients undergoing long-term peritoneal dialysis (PD) therapy.
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Chapter and Conference Paper
The Service Design of Medication Administration System Based on IoT
Medication is the most common way for patients to combat illness, and following the doctor’s advice on taking medication has a tremendous impact on a patient’s healing speed. But due to a variety of conditions...
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Article
Open AccessProtein folding prediction in the HP model using ions motion optimization with a greedy algorithm
The function of a protein is determined by its native protein structure. Among many protein prediction methods, the Hydrophobic-Polar (HP) model, an ab initio method, simplifies the protein folding prediction ...
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Article
Open AccessLongitudinal analysis of cardiac structure and function in incident-automated peritoneal dialysis: comparison between icodextrin solution and glucose-based solution
This study aimed to evaluate the longitudinal changes in cardiac structure and function in incident-automated peritoneal dialysis (APD) patients.
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Article
Open AccessCumulative receiver operating characteristics for analyzing interaction between tissue visfatin and clinicopathologic factors in breast cancer progression
Visfatin has been reported to be associated with breast cancer progression, but the interaction between the visfatin and clinicopathologic factors in breast cancer progression status requires further investiga...
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Article
Open AccessImpact of risk factors on functional status in maintenance hemodialysis patients
To survey by measuring patient’s functional status which is crucial when end-stage renal disease patients begin a dialysis program. The influence of the disease on patients can be examined by the measurement o...
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Article
Open AccessPublisher Correction: Multiobjective differential evolution-based multifactor dimensionality reduction for detecting gene–gene interactions
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
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Article
Open AccessMultiobjective differential evolution-based multifactor dimensionality reduction for detecting gene–gene interactions
Epistasis within disease-related genes (gene–gene interactions) was determined through contingency table measures based on multifactor dimensionality reduction (MDR) using single-nucleotide polymorphisms (SNPs...
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Article
Open AccessMicroRNA-122 as a predictor of HBsAg seroclearance in hepatitis B and C dual infected patients treated with interferon and ribavirin
It has been demonstrated that microRNA-122 (miR-122) plays key roles in the modulation of hepatitis B virus (HBV) replication. This study examined the role of miR-122 in patients with hepatitis C virus (HCV)-H...
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Article
Open AccessAn association between time-varying serum albumin level and the mortality rate in maintenance haemodialysis patients: a five-year clinical cohort study
Until now, no long-term studies relating serum albumin level to mortality rate in prevalent haemodialysis (HD) patients have been conducted. We aimed to examine the association between serum albumin level and ...
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Article
Open AccessAn efficiency analysis of high-order combinations of gene–gene interactions using multifactor-dimensionality reduction
Multifactor dimensionality reduction (MDR) is widely used to analyze interactions of genes to determine the complex relationship between diseases and polymorphisms in humans. However, the astronomical number o...
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Article
Open AccessIdentification of SNP barcode biomarkers for genes associated with facial emotion perception using particle swarm optimization algorithm
Facial emotion perception (FEP) can affect social function. We previously reported that parts of five tested single-nucleotide polymorphisms (SNPs) in the MET and AKT1 genes may individually affect FEP perform...
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Article
Open AccessIdentifying association model for single-nucleotide polymorphisms of ORAI1 gene for breast cancer
ORAI1 channels play an important role for breast cancer progression and metastasis. Previous studies indicated the strong correlation between breast cancer and individual single nucleotide polymorphisms (SNPs) of...
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Article
Open AccessImproved branch and bound algorithm for detecting SNP-SNP interactions in breast cancer
Single nucleotide polymorphisms (SNPs) in genes derived from distinct pathways are associated with a breast cancer risk. Identifying possible SNP-SNP interactions in genome-wide case–control studies is an impo...
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Article
Open AccessURPD: a specific product primer design tool
Polymerase chain reaction (PCR) plays an important role in molecular biology. Primer design fundamentally determines its results. Here, we present a currently available software that is not located in analyzin...
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Article
Open AccessCpGPAP: CpG island predictor analysis platform
Genomic islands play an important role in medical, methylation and biological studies. To explore the region, we propose a CpG islands prediction analysis platform for genome sequence exploration (CpGPAP).
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Article
Open AccessConfronting two-pair primer design for enzyme-free SNP genoty** based on a genetic algorithm
Polymerase chain reaction with confronting two-pair primers (PCR-CTPP) method produces allele-specific DNA bands of different lengths by adding four designed primers and it achieves the single nucleotide polym...
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Article
Open AccessSNP-RFL** 2: an updated and integrated PCR-RFLP tool for SNP genoty**
PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genoty** and mutation detection, but the manual mining for restriction enzyme sites is challenging and cumbersome....