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Article
Open AccessRedox-enabled electronic interrogation and feedback control of hierarchical and networked biological systems
Microelectronic devices can directly communicate with biology, as electronic information can be transmitted via redox reactions within biological systems. By engineering biology’s native redox networks, we ena...
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Article
Open AccessParsed synthesis of pyocyanin via co-culture enables context-dependent intercellular redox communication
Microbial co-cultures and consortia are of interest in cell-based molecular production and even as “smart” therapeutics in that one can take advantage of division of labor and specialization to expand both the...
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Article
Bioelectronic control of a microbial community using surface-assembled electrogenetic cells to route signals
We developed a bioelectronic communication system that is enabled by a redox signal transduction modality to exchange information between a living cell-embedded bioelectronics interface and an engineered micro...
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Article
Open AccessBacterial co-culture with cell signaling translator and growth controller modules for autonomously regulated culture composition
Synthetic biology and metabolic engineering have expanded the possibilities for engineered cell-based systems. The addition of non-native biosynthetic and regulatory components can, however, overburden the rep...
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Article
Open AccessNano-guided cell networks as conveyors of molecular communication
Advances in nanotechnology have provided unprecedented physical means to sample molecular space. Living cells provide additional capability in that they identify molecules within complex environments and actua...