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  1. No Access

    Article

    High-level Sp1 is Associated with Proliferation, Invasion, and Poor Prognosis in Astrocytoma

    Astrocytoma is the most common and the most lethal primary brain tumor in adults. Grade IV glioblastoma is usually refractory to currently available surgical, chemotherapeutic, and radiotherapeutic treatments....

    Yi-Ting Chen, Hung-Pei Tsai, Chun-Chieh Wu, Chiao-Yun Chen… in Pathology & Oncology Research (2019)

  2. No Access

    Article

    Autophagy and Apoptosis Play Opposing Roles in Overall Survival of Esophageal Squamous Cell Carcinoma

    Esophageal cancer is among the most aggressive gastrointestinal tract malignancies, and squamous cell carcinoma is the most common subtype. Although both autophagy and apoptosis involve programmed cell death, ...

    Hsin-I Chen, Hung-Pei Tsai, Yi-Ting Chen, Shu-Chuan Tsao… in Pathology & Oncology Research (2016)

  3. No Access

    Article

    The X-linked inhibitor of apoptosis protein is an independent prognostic marker for rectal adenocarcinoma after preoperative chemoradiotherapy

    Rectal cancer (RC) is a common malignancy of the gastrointestinal tract. Preoperative neoadjuvant concurrent chemoradiotherapy (CCRT) is considered an effective treatment as it down-stages advanced RC. X-linke...

    Yi-Ting Chen, Shu-Chuan Tsao, Hung-Pei Tsai, Jaw-Yuan Wang… in Virchows Archiv (2016)

  4. No Access

    Article

    Serine Protease Inhibitor Kazal Type 1 (SPINK1) Promotes Proliferation of Colorectal Cancer Through the Epidermal Growth Factor as a Prognostic Marker

    Serine protease inhibitor Kazal type-1 (SPINK1), a trypsin kinase inhibitor, is involved in inflammation, cell proliferation and carcinogenesis. The role and association between SPINK1, EGFR and Ki-67 in color...

    Yi-Ting Chen, Shu-Chuan Tsao, Shyng-Shiou F. Yuan… in Pathology & Oncology Research (2015)

  5. No Access

    Article

    Overexpression of Autophagy-Related 16-Like 1 in Patients with Oral Squamous Cell Carcinoma

    Dyregulation of autophagy has been reported in various human cancers including oral squamous cell carcinoma (OSCC). The objective of this study was to link expression of autophagy-related 16-like 1 (ATG16L1), ...

    Jen-Yang Tang, Edward Hsi, Ya-Chun Huang… in Pathology & Oncology Research (2015)

  6. No Access

    Article

    Differential CD133 expression distinguishes malignant from benign papillary lesions of the breast

    Malignant papillary lesions are, in contrast to their benign counterpart, rare malignant tumors in the breast. To differentiate between benign or atypical and malignant papillary lesions can be difficult, espe...

    Chih-Hung Lin, Chia-Hsing Liu, Chien-Hui Wen, Pei-Ling Ko, Chee-Yin Chai in Virchows Archiv (2015)

  7. No Access

    Article

    ATG9A overexpression is associated with disease recurrence and poor survival in patients with oral squamous cell carcinoma

    ATG9A is an integral membrane protein required for autophagosome formation and a membrane carrier in the autophagy pathways. The present study was designed to investigate the expression of ATG9A in oral squamo...

    Jen-Yang Tang, Edward Hsi, Ya-Chun Huang, Nicholas Chung-Heng Hsu… in Virchows Archiv (2013)

  8. No Access

    Article

    Increased CD133 expression after preoperative chemoradiotherapy in rectal cancers other than mucin-rich tumors

    This study is to characterize the sequential change in CD133 expression after preoperative chemoradiotherapy (CRT) in rectal cancer and its impact on postoperative prognosis. Forty-one patients with rectal can...

    Chih-Hung Lin, Wan-Tzu Chen, Chia-Hsing Liu, Hung-Pei Tsai… in Virchows Archiv (2012)