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Article
Open AccessA software solution for recording circadian oscillator features in time-lapse live cell microscopy
Fluorescent and bioluminescent time-lapse microscopy approaches have been successfully used to investigate molecular mechanisms underlying the mammalian circadian oscillator at the single cell level. However, ...
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Protocol
Circadian Lipidomics: Analysis of Lipid Metabolites Around the Clock
Lipidomics has been defined as the large-scale analysis of lipids in organelles, cells, tissues, or whole organisms. Including the temporal aspects of lipid metabolic changes into this analysis allows to acces...
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Article
Open AccessClass 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesis
Metabolic demands fluctuate rhythmically and rely on coordination between the circadian clock and nutrient-sensing signalling pathways, yet mechanisms of their interaction remain not fully understood. Surprisi...