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  1. Article

    Open Access

    Validation of MSIntuit as an AI-based pre-screening tool for MSI detection from colorectal cancer histology slides

    Mismatch Repair Deficiency (dMMR)/Microsatellite Instability (MSI) is a key biomarker in colorectal cancer (CRC). Universal screening of CRC patients for MSI status is now recommended, but contributes to incre...

    Charlie Saillard, Rémy Dubois, Oussama Tchita, Nicolas Loiseau in Nature Communications (2023)

  2. Article

    Open Access

    Pacpaint: a histology-based deep learning model uncovers the extensive intratumor molecular heterogeneity of pancreatic adenocarcinoma

    Two tumor (Classical/Basal) and stroma (Inactive/active) subtypes of Pancreatic adenocarcinoma (PDAC) with prognostic and theragnostic implications have been described. These molecular subtypes were defined by...

    Charlie Saillard, Flore Delecourt, Benoit Schmauch in Nature Communications (2023)

  3. Article

    Open Access

    A deep learning model to predict RNA-Seq expression of tumours from whole slide images

    Deep learning methods for digital pathology analysis are an effective way to address multiple clinical questions, from diagnosis to prediction of treatment outcomes. These methods have also been used to predic...

    Benoît Schmauch, Alberto Romagnoni, Elodie Pronier in Nature Communications (2020)