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    Article

    Comparative efficacy of liposomes containing synthetic bacterial cell wall analogues for tumoricidal activation of monocytes and macrophages

    We examined the activation to the tumoricidal state of normal mouse peritoneal exudate macrophages, bone marrow macrophages, and human blood monocytes by liposomes containing either lipophilic muramyl tripepti...

    Teruhiro Utsugi, Akihiko Nii, Dominic Fan in Cancer Immunology, Immunotherapy (1991)

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    Liposomal delivery of biological response modifiers to macrophages

    Macrophages activated to the tumoricidal state can recognize and destroy neoplastic cells and leave normal cells unharmed. Systemic activation of macrophages can be achieved by the intravenous administration o...

    Charles C. Pak, Isaiah J. Fidler in Biotherapy (1991)

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    Macrophages and cancer

    The uncontrolled growth of metastases resistant to conventional therapeutic modalities is a major cause of death from cancer. Data from our laboratory and others indicate that metastases arise from the nonrand...

    Pat W. Whitworth, Charles C. Pak, Joseph Esgro in Cancer and Metastasis Reviews (1990)